Evidence map›Paper›PMID 42666736›Full record

ArticleAutophagy reports2026

A metabolic entry point into micro-chlorophagy: insights from impaired maltose metabolism.

Sakuya Nakamura, Shinya Hagihara, Masanori Izumi

Abstract read
In one paragraph

Article in Autophagy reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sakuya NakamuraRIKEN Center for Sustainable Resource Science (CSRS), Wako, Japan.ORCID https://orcid.org/0000-0002-8218-6894
Shinya HagiharaRIKEN Center for Sustainable Resource Science (CSRS), Wako, Japan.ORCID https://orcid.org/0000-0003-0348-7873
Masanori IzumiRIKEN Center for Sustainable Resource Science (CSRS), Wako, Japan.ORCID https://orcid.org/0000-0001-5222-9163

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the site of photosynthesis and carbohydrate metabolism, chloroplasts are essential for phototrophic plant growth. The selective elimination of damaged chloroplasts by autophagy, a process known as chlorophagy, is crucial for chloroplast quality control. However, the mechanisms that activate chlorophagy and that underline its specificity remain poorly understood. Our recent study identified changes in maltose metabolism as a previously unrecognized trigger of a micro-chlorophagy program that depends on components of the core autophagy machinery. These findings provide a new starting point for uncovering the molecular principles that govern micro-chlorophagy. Here, we discuss emerging evidence showing that metabolic changes induce autophagic chloroplast turnover and outline the key challenges in defining the signals that initiate micro-chlorophagy.

Indexed as

Arabidopsisautophagychlorophagychloroplastmaltose metabolismplant

Identifiers

PMID42666736
PMCPMC13523917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.