Evidence map›Paper›PMID 42666713›Full record

ArticleJournal of skin cancer2026

Postoperative Margin Management After Conventional Excision of Facial Basal and Squamous Cell Carcinomas: A Histotype-Specific Framework.

Flavio Perottino, Stefano Ottoboni, Giulia Dalmasso, Katia Barbaro, Daniele Sagrafoli, Paola Ghisellini, Cristina Rando, Roberto Eggenhöffner, Mario Borgione

Abstract read
In one paragraph

Article in Journal of skin cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Flavio PerottinoDepartment of ENT and Stomatology, Centre Hospitalier des Escartons, Briancon, France.ORCID https://orcid.org/0000-0002-8303-346X
Stefano OttoboniDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy, unige.it.ORCID https://orcid.org/0000-0002-1909-5949
Giulia DalmassoDepartment of ENT and Stomatology, Centre Hospitalier des Escartons, Briancon, France.ORCID https://orcid.org/0009-0006-8814-4149
Katia BarbaroExperimental Zooprophylactic Institute of Lazio and Tuscany, Rome, Italy.ORCID https://orcid.org/0000-0001-9830-996X
Daniele SagrafoliExperimental Zooprophylactic Institute of Lazio and Tuscany, Rome, Italy.ORCID https://orcid.org/0009-0003-4088-8753
Paola GhiselliniDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy, unige.it.ORCID https://orcid.org/0000-0003-0505-0106
Cristina RandoDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy, unige.it.ORCID https://orcid.org/0000-0003-2575-0257
Roberto EggenhöffnerDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy, unige.it.ORCID https://orcid.org/0000-0001-7886-1829
Mario BorgioneDepartment of ENT and Stomatology, Centre Hospitalier des Escartons, Briancon, France.ORCID https://orcid.org/0009-0001-4265-8519

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Postoperative management of close or positive margins after conventional excision of facial nonmelanoma skin cancer is challenging, especially in elderly patients and anatomically constrained sites where re-excision may impose functional or aesthetic morbidity. Methods: We retrospectively analysed 238 facial carcinoma cases treated by conventional excision at a peripheral ENT unit, including 172 basal cell carcinomas (BCC) and 66 squamous cell carcinomas (SCC). Margins were classified as clear, close or positive. Outcomes were analysed descriptively; two-sided Fisher exact tests were used as exploratory descriptors of distributional imbalance under sparse-event conditions, not as tests of treatment superiority or equivalence. Results: In BCC, no recurrence occurred after clear margins (0/90). Among non-clear-margin BCCs, recurrence remained uncommon after structured surveillance (5/65) and early re-excision (1/17). In SCC, recurrence occurred only after positive margins (3/15), with none after clear or close margins. Conclusion: The findings support histotype-specific postoperative interpretation of margin status after conventional facial skin cancer excision. In this cohort, selected lower-risk BCC cases were managed through structured surveillance, whereas SCC recurrence was confined to positive-margin cases, supporting a lower threshold for timely re-excision or equivalent oncologic management when clinically feasible.

Indexed as

basal cell carcinomaconventional excisionfacial reconstructionnon-melanoma skin cancerpostoperative surveillancerecurrenceskin cancersquamous cell carcinomasurgical margins

Identifiers

PMID42666713
PMCPMC13522925

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.