Evidence map›Paper›PMID 42666602›Full record

ArticleHeart rhythm O22026

Atrial fibrillation ablation in patients with hypertrophic cardiomyopathy: Findings and outcomes of repeat ablation procedures.

Jose F de Melo Junior, Daniella Haas, William H Swain, Shahid Karim, Samuel J Asirvatham, Freddy M Del-Carpio, Abhishek J Deshmukh, Christopher V DeSimone, Fatima M Ezzeddine, Paul A Friedman and 9 more

Abstract read
In one paragraph

Article in Heart rhythm O2, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jose F de Melo JuniorDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Daniella HaasMayo Clinic Alix School of Medicine, Rochester, Minnesota.
William H SwainDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Shahid KarimDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Samuel J AsirvathamDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Freddy M Del-CarpioDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Abhishek J DeshmukhDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Christopher V DeSimoneDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Fatima M EzzeddineDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Paul A FriedmanDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Suraj KapaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Ammar M KilluDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Gurukripa G KowlgiDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Malini MadhavanDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Siva K MulpuruDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Peter A NoseworthyDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Alan M SugrueDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Nicholas Y TanDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Konstantinos C SiontisDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with atrial fibrillation (AF) and hypertrophic cardiomyopathy (HCM) commonly require repeat catheter ablation procedures for AF management. The mechanisms underlying the increased AF recurrence rates are poorly defined. Objective: We aimed to explore mapping findings and ablation outcomes among patients with HCM undergoing repeat AF ablation. Methods: In this single-center study, 45 patients with HCM underwent repeat AF ablation procedures (2015-2023). Patients were age- and sex-matched 1:1 to control patients without HCM undergoing repeat AF ablation. Details from comprehensive electroanatomic mapping were compared. Univariate and multivariate Cox regression analyses were used to evaluate prognostic factors for recurrent AF in HCM. Results: The mean age in the HCM group was 57.5 ± 13.2 and 71% were male. The most common finding at repeat ablation was pulmonary vein (PV) reconnection (86.7% in the HCM group vs 75.5% in the control group, Conclusion: PV reconnection is commonly observed in patients with HCM undergoing repeat AF ablation. Repeat AF ablation outcomes in patients with HCM were comparable to those in patients without HCM.

Indexed as

Atrial fibrillationCatheter ablationHypertrophic cardiomyopathyOutcomesPulmonary vein isolationRecurrence

Identifiers

PMID42666602
PMCPMC13523576

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.