ArticleUrology case reports2026
Catastrophic systemic reaction and fatal disseminated intravascular coagulation following high-pressure intrapelvic povidone-iodine instillation: A case report and review of possible mechanisms.
Article in Urology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
High-pressure intrapelvic instillation of povidone-iodine may result in catastrophic systemic complications, although such events are rarely reported. We describe a 52-year-old woman with genitourinary tuberculosis and a solitary functioning kidney who underwent augmentation cystoplasty with ureteric reimplantation. During surgery, dilute povidone-iodine was instilled through a percutaneous nephrostomy under high pressure to identify the ureteric orifice. Within minutes, she developed a catastrophic systemic reaction followed by disseminated intravascular coagulation, refractory shock, and death despite aggressive resuscitation and re-exploration. This case highlights the potential hazards of high-pressure intrapelvic antiseptic instillation and discusses possible underlying mechanisms.
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