Evidence map›Paper›PMID 42666564›Full record

ArticleCase reports in plastic surgery & hand surgery2026

Salvage reconstruction of an irradiated and infected scalp-calvarial defect following recurrent atypical meningioma: recipient-vessel strategy and multidisciplinary decision-making.

Federico Ziani, Sofia De Riso, Silvia Vacca, Matteo Garassino, Paola Pentangelo, Anna Manconi, Michail Sorotos, Sabino Luzzi, Corrado Rubino, Emilio Trignano

Abstract readCase Reports
In one paragraph

Article in Case reports in plastic surgery & hand surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Federico ZianiDepartment of Medical, Surgical and Experimental Sciences, Plastic Surgery Unit, Sassari University Hospital Trust, University of Sassari, Sassari, Italy.
Sofia De RisoDepartment of Medical, Surgical and Experimental Sciences, Plastic Surgery Unit, Sassari University Hospital Trust, University of Sassari, Sassari, Italy.
Silvia VaccaDepartment of Medical, Surgical and Experimental Sciences, Plastic Surgery Unit, Sassari University Hospital Trust, University of Sassari, Sassari, Italy.
Matteo GarassinoDepartment of Medical, Surgical and Experimental Sciences, Plastic Surgery Unit, Sassari University Hospital Trust, University of Sassari, Sassari, Italy.
Paola PentangeloPlastic Surgery Unit, Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy.
Anna ManconiDepartment of Medical, Surgical and Experimental Sciences, Plastic Surgery Unit, Sassari University Hospital Trust, University of Sassari, Sassari, Italy.
Michail SorotosDepartment of Plastic and Reconstructive Surgery, Sant'Andrea Hospital, NESMOS (Neurosciences, Mental Health and Sensory Organs) Department, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.
Sabino LuzziDepartment of Neurosurgery, Azienda Ospedaliero-Universitaria di Sassari, Sassari, Italy.
Corrado RubinoDepartment of Medical, Surgical and Experimental Sciences, Plastic Surgery Unit, Sassari University Hospital Trust, University of Sassari, Sassari, Italy.
Emilio TrignanoDepartment of Medical, Surgical and Experimental Sciences, Plastic Surgery Unit, Sassari University Hospital Trust, University of Sassari, Sassari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reconstruction of complex scalp defects associated with calvarial involvement represents a significant challenge, particularly in patients who have undergone radiotherapy, experienced infection and undergone multiple surgical procedures. In these settings, locoregional reconstructive options are often unreliable and free tissue transfer plays a central role in achieving stable, well-vascularized coverage. We present a case of a 50-year-old woman with recurrent atypical meningioma who underwent multiple neurosurgical resections and radiotherapy. The postoperative course was complicated by wound dehiscence, infection, and cranioplasty failure. Upon evaluation, the patient exhibited a large posterior scalp defect (14 × 5 cm) with exposed calvarium. A multidisciplinary approach was adopted. Following neurosurgical debridement, tumor resection and calvarial reconstruction using a titanium mesh, soft-tissue coverage was achieved with a free latissimus dorsi muscle flap combined with a split-thickness skin graft. Microvascular anastomosis was performed using the superior thyroid artery and the jugular venous system, selected outside the irradiated field. The postoperative course was uneventful, with no signs of flap ischemia or venous congestion. At eight months of follow-up, the patient demonstrated complete wound healing, stable coverage, and a satisfactory morphofunctional outcome, with minimal donor-site morbidity. This report emphasizes that successful salvage reconstruction of irradiated scalp defects complicated by osteomyelitis depends not only on vascularized tissue transfer but also on meticulous recipient vessel selection. In particular, the superior thyroid artery represented a reliable recipient vessel outside the irradiated field, allowing safe microvascular reconstruction despite previous surgery, infection and radiation-induced vascular compromise.

Indexed as

calvarial reconstructionlatissimus dorsi free flapmicrosurgeryRecurrent meningiomascalp reconstruction

Identifiers

PMID42666564
PMCPMC13523118

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