Evidence map›Paper›PMID 42666556›Full record

ArticleCureus2026

Disseminated Septic Emboli From Aortic Valve Infective Endocarditis in an Immunocompromised Patient: A Case Report.

Mandeep Singh, Sharmila Seeralan, Mayuran Seeralan, Olanrewaju Oladipo

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mandeep SinghGeneral Internal Medicine, Princess Alexandra Hospital, Harlow, GBR.
Sharmila SeeralanGeneral Internal Medicine, Princess Alexandra Hospital, Harlow, GBR.
Mayuran SeeralanGeriatrics, Princess Alexandra Hospital NHS Trust, Harlow, GBR.
Olanrewaju OladipoGeneral Internal Medicine, Princess Alexandra Hospital, Harlow, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disseminated sepsis with septic embolic disease can present with a wide spectrum of clinical manifestations and may closely mimic metastatic malignancy or immune-related adverse events in oncology patients. We report the case of a 50-year-old woman with cervical squamous cell carcinoma receiving pembrolizumab and infliximab who presented with fever, progressive blistering skin lesions, non-pruritic rash, and new right-sided neurological deficits. Initial concerns included toxic epidermal necrolysis, immunotherapy-related toxicity, metastatic disease, and severe infection. Examination revealed haemorrhagic blisters involving the fingers and toes, truncal rash, and transient right-sided weakness. Blood investigations demonstrated markedly elevated inflammatory markers. Imaging showed a cavitating left lower lobe lung lesion with air-fluid level, bilateral pulmonary infiltrates, hepatic lesions, and ring-enhancing lesions within the left frontal and parietal lobes concerning for cerebral abscesses or metastases. MRI brain findings favoured cerebral abscesses with surrounding vasogenic oedema. Wound cultures from hand and foot lesions grew

Indexed as

cancer immunotherapycerebral abscessimmunosuppressioninfective endocarditisseptic emboli

Identifiers

PMID42666556
PMCPMC13522966

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.