Evidence map›Paper›PMID 42666374›Full record

ArticleJournal of the American College of Emergency Physicians open2026

Emergency Department Syphilis Screening: Insights from a National Stakeholder Convening.

Kimberly A Stanford, Elissa M Shechter-Perkins, Douglas White, Stephen Contag, Shannon Dowler, Herbert Duber, Kiran Faryar, Jason Haukoos, Rebekah Horowitz, Katherine Hsu and 3 more

Abstract read
In one paragraph

Article in Journal of the American College of Emergency Physicians open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kimberly A StanfordSection of Emergency Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
Elissa M Shechter-PerkinsDepartment of Emergency Medicine, Boston Medical Center, Boston, Massachusetts, USA.
Douglas WhiteDepartment of Emergency Medicine, Alameda Health System - Highland Hospital, Oakland, California, USA.
Stephen ContagDepartment of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, Minnesota, USA.
Shannon DowlerMecklenburg County Health Department, Charlotte, North Carolina, USA.
Herbert DuberDepartment of Emergency Medicine, University of Washington, Seattle, Washington, USA.
Kiran FaryarDepartment of Emergency Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Jason HaukoosDepartment of Emergency Medicine, Denver Health, Denver, Colorado, USA.
Rebekah HorowitzNational Association of County & City Health Officials, Washington, DC, USA.
Katherine HsuDepartment of Pediatrics, Boston Medical Center, Boston, Massachusetts, USA.
Jesse PinesUS Acute Care Solutions, Canton, Ohio, USA.
Jason ZuckerDivision of Infectious Diseases, Columbia University, New York, New York, USA.
Michael S LyonsDepartment of Emergency Medicine, The Ohio State Medical Center, Columbus, Ohio, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The United States is experiencing a prolonged syphilis epidemic, with high rates of infection and increasing cases of congenital syphilis. Despite these trends, there is no coordinated national approach to syphilis screening outside of pregnancy, and many individuals at highest risk lack access to routine outpatient care. Emergency departments (EDs), which serve as a critical safety net for populations at highest risk of syphilis and its complications, represent an important and underutilized setting for syphilis screening. To address this gap, a national convening of multidisciplinary experts was organized by the Emergency Medicine Transmissible Infectious Diseases and Epidemics consortium, with support from the Centers for Disease Control and Prevention and the National Association of County and City Health Officials. Participants reviewed available evidence and shared implementation experience to identify feasible and effective strategies for ED-based syphilis screening. Inperson discussion was followed by iterative review and revision of manuscript drafts until consensus was achieved. A tiered framework for ED syphilis screening is proposed, including universal, population-focused, and minimum screening strategies, allowing adaptation to local resources and epidemiology. Key operational considerations include consent processes, laboratory testing approaches, electronic health record integration, and systems for follow-up and treatment. Successful implementation requires infrastructure beyond the ED, including partnerships with public health agencies, supportive policy, and sustainable financing. ED-based syphilis screening represents a critical opportunity to improve early detection, reduce transmission, and prevent congenital syphilis. Coordinated national guidance and investment are needed to support widespread adoption and maximize public health impact.

Identifiers

PMID42666374
PMCPMC13522367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.