Evidence map›Paper›PMID 42666372›Full record

ArticleBioactive materials2027

Synergistic antibacterial and osteogenic properties of micro-arc oxidation GO@Ag/SF composite coatings for the repair of infectious bone defects.

Wanliang Yang, Jingwei Bi, Xinxin Ji, Tian Bai, Zehao Jing, Xingkun Wang, Haoran Chang, Qian Xu, Junhao Lin, Jiguang Tian and 5 more

Abstract read
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In one paragraph

Article in Bioactive materials, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Wanliang YangDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, China.
Jingwei BiDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, China.
Xinxin JiDepartment of General Practice, Binzhou People's Hospital, Binzhou, China.
Tian BaiShaanxi Key Laboratory of Biomedical Metallic Materials, Northwest Institute for Non-ferrous Metal Research, Xian, 710016, China.
Zehao JingDepartment of Orthopedics, Peking University Third Hospital, Beijing, 100191, China.
Xingkun WangDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, China.
Haoran ChangDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, China.
Qian XuDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, China.
Junhao LinDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, China.
Jiguang TianDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, China.
Kai DiDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, China.
Xin PanDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, China.
Wenhao ZhouShaanxi Key Laboratory of Biomedical Metallic Materials, Northwest Institute for Non-ferrous Metal Research, Xian, 710016, China.
Hao LiDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, China.
Teng ZhangDepartment of Orthopedics, Qilu Hospital of Shandong University, Jinan, 250012, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bacterial infection and insufficient osseointegration of titanium-based implants remain major clinical challenges. Conventional drug-loaded coatings often fail to simultaneously achieve long-term antibacterial activity and the construction of an osteogenic microenvironment. Methods: In this study, a graphene oxide-supported silver nanoparticle/silk fibroin (GO@Ag/SF) composite coating was developed and modified via micro-arc oxidation. By precisely controlling the GO/AgNO Results: The optimized GO@Ag-2/SF coating exhibited pH-responsive sustained Ag Conclusion: Through the synergistic effects of its components, the GO@Ag/SF coating established a dynamic antibacterial-osteogenic balance, offering a promising strategy for the repair of infectious bone defects.

Indexed as

Graphene oxide-silver nanocompositeInfected bone defectOsteogenic microenvironmentpH/NIR-responsive antibacterialToxicity mitigation effect

Identifiers

PMID42666372
PMCPMC13522243

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.