ArticleFrontiers in medicine2026
Atypical mitral valve infective endocarditis presenting with fever and left upper abdominal pain due to splenic infarction: a case report.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Infective endocarditis (IE) may present with non-specific systemic symptoms and embolic complications, making early diagnosis challenging, particularly when initial transthoracic echocardiography (TTE) is non-diagnostic. We report a case of atypical mitral valve IE in a 40-year-old man who presented with persistent fever and left upper abdominal pain rather than overt cardiac symptoms. On admission, inflammatory markers were elevated, whereas emergency chest and abdominal computed tomography showed no definite acute infectious focus. Initial TTE demonstrated only mild mitral and tricuspid regurgitation, with no definite vegetation. However, bedside cardiac auscultation identified a grade 3-4/6 systolic murmur at the mitral area, prompting further investigation. Contrast-enhanced abdominal magnetic resonance imaging subsequently revealed splenic infarction, indicating an embolic event. Blood cultures from both aerobic and anaerobic bottles grew
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