ArticleBMC nephrology2026
95% ethanol rinse combined with lauromacrogol injection versus lauromacrogol injection alone for ultrasound-guided percutaneous sclerotherapy of simple renal cysts in elderly patients: Which is safer and more effective?
Article in BMC nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
objectiveTo compare the efficacy and safety of 95% ethanol rinse combined with lauromacrogol injection versus lauromacrogol injection alone in sclerotherapy for simple renal cysts in elderly patients.
methodsThis retrospective analysis included 94 patients (63 males, 31 females; mean age, 70.15 years) with symptomatic simple renal cysts who underwent ultrasound-guided percutaneous sclerotherapy between 2019 and 2025. Forty-eight patients received lauromacrogol injection alone, while 46 patients received 95% ethanol rinse combined with lauromacrogol injection. All patients were followed up at 1, 6, and 12 months after the procedure.
resultsThe volume of simple renal cysts decreased during follow-up, from a mean initial volume of 113.2 mL to a final volume of 0.30 mL. At 12 months, the total resolution rate was 98.9% (93/94), and the cure rate was 97.9% (92/94). No significant differences were observed between the two groups in volume reduction rate, resolution rate, or cure rate during follow-up (all P > 0.05). The adverse event rate was significantly higher in the ethanol-combination group than in the lauromacrogol-monotherapy group (56.5% [26/46] vs. 29.2% [14/48]; P < 0.05). Ethanol use was associated with significantly more pain and a higher incidence of fever, even when limited to rinsing the cyst lumen prior to lauromacrogol injection.
conclusionPercutaneous sclerotherapy was successful in both groups of elderly patients with simple renal cysts. Lauromacrogol injection alone was associated with a significantly lower incidence of minor adverse events. CLINICAL TRIAL NUMBER: Not applicable.
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