Evidence map›Paper›PMID 42665385›Full record

ArticleIn vivo (Athens, Greece)

Microbiological Profiles of Suspected Postoperative Pneumonia After Esophagectomy: A Focus on Gram-negative Pathogens.

Takeshi Matsubara, Hiroki Okamura, Kana Fujihara, Kento Nakajima, Yuto Yasuda, Koki Kawakami, Yuriko Yamada, Kazunari Ishitobi, Shunsuke Kaji, Takahito Taniura and 3 more

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Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

13 authors.

Takeshi MatsubaraDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan nanadai@med.shimane-u.ac.jp.
Hiroki OkamuraDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Kana FujiharaDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Kento NakajimaDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Yuto YasudaDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Koki KawakamiDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Yuriko YamadaDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Kazunari IshitobiDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Shunsuke KajiDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Takahito TaniuraDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Takayuki TanakaDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Tetsu YamamotoDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Masaaki HidakaDepartment of Digestive and General Surgery, Shimane University Faculty of Medicine, Izumo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPostoperative pneumonia is an important complication after esophagectomy for esophageal cancer. Although sputum cultures are often obtained when pneumonia is suspected, the microbiological profiles detected in this setting remain insufficiently characterized. This study aimed to describe sputum culture findings at suspected postoperative pneumonia onset, focusing on Gram-negative organisms and targetable pathogens relevant to antimicrobial selection. PATIENTS AND

methodsWe retrospectively reviewed 150 consecutive patients who underwent esophagectomy for esophageal cancer between January 2014 and April 2026. Patients were classified into early video-assisted thoracoscopic (VATS) esophagectomy, robot-assisted minimally invasive esophagectomy (RAMIE), and late VATS esophagectomy groups. Clinically relevant postoperative pneumonia was defined as Clavien-Dindo grade II or higher pneumonia within 30 days after surgery. Sputum cultures obtained at suspected pneumonia onset were reviewed.

resultsA significantly higher incidence of pneumonia was observed in the RAMIE group (44.4%) compared to the early (19.0%) and late (24.2%) VATS groups (

conclusionSputum cultures, after esophagectomy, obtained at suspected postoperative pneumonia onset frequently revealed Gram-negative organisms and targetable pathogens. These findings provide a clinical basis for empirical antimicrobial selection and subsequent de-escalation strategies, but detected organisms should be interpreted as organism distribution rather than definitive causative pathogens.

Indexed as

Esophageal NeoplasmsEsophagectomyGram-Negative BacteriaPneumoniaPneumonia, BacterialPostoperative ComplicationsAgedAnti-Bacterial AgentsFemaleHumansMaleMiddle AgedRetrospective StudiesSputumAnti-Bacterial Agentsantimicrobial stewardshipEsophageal canceresophagectomyGram-negative bacteriapostoperative pneumoniasputum culture

Identifiers

PMID42665385
PMCPMC13531129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.