Evidence map›Paper›PMID 42665383›Full record

ArticleIn vivo (Athens, Greece)

Impact of Non-curative Endoscopic Submucosal Dissection on Minimally Invasive Distal Gastrectomy and on Robotic

Yuma Ebihara, Daisuke Saikawa, Yuki Okawa, Yume Okuda, Sho Sekiya, Toshihiro Kushibiki, Koichi Teramura, Yoshinori Suzuki, Tetsuya Sumiyoshi, Y O Kawarada and 3 more

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Yuma EbiharaDepartment of Surgery, Tonan Hospital, Sapporo, Japan; yuma.ebihara@tonan.gr.jp.
Daisuke SaikawaDepartment of Surgery, Tonan Hospital, Sapporo, Japan.
Yuki OkawaDepartment of Surgery, Tonan Hospital, Sapporo, Japan.
Yume OkudaDepartment of Surgery, Tonan Hospital, Sapporo, Japan.
Sho SekiyaDepartment of Surgery, Tonan Hospital, Sapporo, Japan.
Toshihiro KushibikiDepartment of Surgery, Tonan Hospital, Sapporo, Japan.
Koichi TeramuraDepartment of Surgery, Tonan Hospital, Sapporo, Japan.
Yoshinori SuzukiDepartment of Surgery, Tonan Hospital, Sapporo, Japan.
Tetsuya SumiyoshiDepartment of Gastroenterology, Tonan Hospital, Sapporo, Japan.
Y O KawaradaDepartment of Surgery, Tonan Hospital, Sapporo, Japan.
Shuji KitashiroDepartment of Surgery, Tonan Hospital, Sapporo, Japan.
Shunichi OkushibaDepartment of Surgery, Tonan Hospital, Sapporo, Japan.
Satoshi HiranoDepartment of Gastroenterological Surgery II, Faculty of Medicine, Hokkaido University, Sapporo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThe impact of prior non-curative endoscopic submucosal dissection (ESD) on the safety and oncological adequacy of minimally invasive distal gastrectomy (MIDG) for pT1 gastric cancer is uncertain. Comparative evidence for laparoscopic PATIENTS AND

methodsWe retrospectively reviewed 169 patients with pT1 gastric cancer who underwent MIDG at a single center between April 2018 and December 2024; 43 had undergone non-curative ESD. Propensity score-matching produced 33 matched pairs for the primary comparison between patients with and without prior ESD. Perioperative metrics and early oncological outcomes were assessed. Perioperative and short-term oncological outcomes were compared between laparoscopic (n=33) and robotic (n=10) MIDG groups within the post-ESD cohort.

resultsAfter matching, operative duration, estimated blood loss, postoperative complication rates, and length of hospital stay were similar for the ESD and non-ESD groups. The ESD group showed a modest reduction in lymph node yield, but all resections were R0 and there were no recurrences; overall and relapse-free survival were comparable. In the post-ESD subgroup, the robotic approach required a longer operative time, largely due to docking and intracorporeal reconstruction; blood loss, lymphadenectomy yield, morbidity, and hospital stay were comparable to the laparoscopic approach. No disease recurrence was observed after either surgical approach during the follow-up period.

conclusionPrior non-curative ESD did not appear to compromise perioperative safety or early oncological outcomes after MIDG for pT1 gastric cancer. Robotic MIDG is feasible following ESD and provides perioperative and short-term oncological outcomes comparable to laparoscopy; however, the small sample size of the robotic subgroup limits definitive conclusions. Larger prospective studies are warranted to confirm our findings and to clarify the role of robotic platforms in individualized lymphadenectomy after ESD.

Indexed as

Endoscopic Mucosal ResectionGastrectomyLaparoscopyMinimally Invasive Surgical ProceduresRobotic Surgical ProceduresStomach NeoplasmsAgedFemaleHumansLength of StayMaleMiddle AgedNeoplasm StagingPostoperative ComplicationsRetrospective StudiesTreatment Outcomeearly gastric cancerendoscopic submucosal dissectionMinimally invasive distal gastrectomyperioperative morbidity

Identifiers

PMID42665383
PMCPMC13531130

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.