Evidence map›Paper›PMID 42664345›Full record

ArticleScience advances2026

Cryo-EM structures of Cdr1 reveal snapshots of substrate transport and diverse inhibitor recognition.

Zhen Wang, Shuting Yang, Binyu Zhang, Hengyi Jiang, Yinxia Li, Rongchao Gao, Yulong Wang, Fengying Fan, Lili Dong, Jiaxuan Qiu and 4 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zhen WangState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.ORCID 0000-0003-0920-3173
Shuting YangState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.ORCID 0009-0003-9022-1156
Binyu ZhangState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.ORCID 0009-0009-2383-6816
Hengyi JiangShanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China.ORCID 0000-0003-2884-2296
Yinxia LiSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, China.ORCID 0009-0003-7025-0419
Rongchao GaoCryo-Electron Microscopy Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Yulong WangState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Fengying FanState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Lili DongState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.ORCID 0000-0002-8740-079X
Jiaxuan QiuState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Xiurui LiState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.ORCID 0009-0000-4072-6509
Yue ZhouCryo-Electron Microscopy Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Alastair I H MurchieShanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China.ORCID 0000-0002-6746-6054
Xuekui YuState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.ORCID 0000-0002-4434-2040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In

Indexed as

Candida albicansCryoelectron MicroscopyFungal ProteinsMembrane Transport ProteinsAdenosine TriphosphateAntifungal AgentsBinding SitesBiological TransportModels, MolecularProtein BindingProtein ConformationSubstrate SpecificityAdenosine TriphosphateAntifungal AgentsCDR1 protein, Candida albicansFungal ProteinsMembrane Transport Proteins

Identifiers

PMID42664345
PMCPMC13524022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.