Evidence map›Paper›PMID 42664202›Full record

ArticlePloS one2026

AI-assisted forecasting in microsurgery: A dual-component framework for global publication trends.

Georgios Bouloukakis, Georgios Karamitros, Gregory A Lamaris, Wesley P Thayer, Galen Perdikis, Feng Zhang, William C Lineaweaver

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Georgios BouloukakisDepartment of Surgery, SUNY Downstate Health Sciences University, Brooklyn, New York, United States of America.ORCID https://orcid.org/0009-0003-4954-8229
Georgios KaramitrosDepartment of Plastic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.ORCID https://orcid.org/0000-0002-2208-8539
Gregory A LamarisDivision of Plastic and Reconstructive Surgery, R. Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Baltimore, Maryland, United States of America.
Wesley P ThayerDepartment of Plastic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Galen PerdikisDepartment of Plastic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Feng ZhangDepartment of Plastic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
William C LineaweaverDepartment of Plastic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI)-assisted approaches may allow surgical research trends to be analyzed at scale and projected over time. However, their use in forecasting the evolution of microsurgical scholarship remains limited. This study developed an AI-assisted bibliometric framework to characterize and project global clinical and experimental microsurgery publication trends.

methodsPubMed metadata from 20 microsurgery-relevant surgical journals were extracted for 2010-2024 using an automated Python-based retrieval algorithm. A rule-based contextual key-word classifier using a predefined microsurgery keyword taxonomy was applied to identify relevant publications. Candidate forecasting models included linear regression, quadratic regression, autoregressive integrated moving average, and Holt's exponential smoothing. Model performance was compared using R2, root mean square error, mean absolute error, and Akaike information criterion. Forecasts were generated through 2030 and reported with 95% confidence intervals.

resultsThe framework processed 90,902 records, of which 83,133 underwent contextual text classification after exclusion of incomplete metadata. A final analytic dataset of 11,561 microsurgery publications with verifiable first-author country attribution was identified. Classification validation using a stratified sample of 4,441 records demonstrated 95.2% agreement with the human-reviewed reference standard (95% CI, 94.5%-95.8%; Cohen's κ = 0.826). Annual microsurgery publications increased from 611 in 2010-973 in 2024, representing a 59.3% increase. Temporal validation supported short-horizon stability of the linear projection model. In fixed temporal holdout testing, the linear model achieved RMSE 40.5, MAE 36.2, MAPE 4.0%, and 95% prediction-interval coverage of 100%. Through 2030, publication activity is projected to increase, with lymphatic microsurgery showing the greatest relative thematic growth (+36.0%), followed by technological and operative innovation (+21.7%).

conclusionThis study presents an AI-assisted bibliometric workflow for characterizing and projecting microsurgical publication trends. By integrating automated PubMed metadata extraction, contextual keyword-based classification, human-reviewed validation, and conventional statistical forecasting, the workflow enables reproducible assessment of publication activity across time, geography, authorship, and thematic domains. The resulting estimates should be interpreted as conditional projections under observed historical trends rather than deterministic predictions of future scientific activity, innovation, or leadership. This approach may assist surgeons, clinician-scientists, and interdisciplinary research teams in summarizing research patterns, identifying areas of increasing scholarly activity, and informing future collaborative planning.

Indexed as

Artificial IntelligenceMicrosurgeryPublicationsAlgorithmsBibliometricsForecastingHumansPrediction AlgorithmsPubMed

Identifiers

PMID42664202
PMCPMC13524238

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.