Evidence map›Paper›PMID 42663888›Full record

ArticleJournal of clinical psychology in medical settings2026

Treating Multiple Chemical Sensitivity as a Specific Phobia Using Cognitive Behavioural Therapy: A Case Study in an Older Adult.

Matthew Wilcock, Alice Loyal, David Hitt

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Article in Journal of clinical psychology in medical settings, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Matthew WilcockCardiff University, Cardiff, United Kingdom. wilcockm@cardiff.ac.uk.
Alice LoyalCardiff Vale University Health Board, Cardiff, United Kingdom.
David HittCardiff University, Cardiff, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple Chemical Sensitivity (MCS) is a poorly understood condition characterised by physical symptoms triggered by minimal exposure to odorous or chemical agents, often without identifiable organic pathology. This case study describes cognitive behavioural therapy (CBT) for MCS in an older adult referred to a respiratory team after developing persistent, generalised reactions to odours following an acute toxic inhalation. Symptoms led to severe avoidance, functional impairment and suicidal ideation. Following medical evaluation, psychological assessment did not support the alternative diagnoses considered and informed a working formulation of specific phobia. Treatment comprised 14 sessions, beginning virtually because of avoidance, progressing to in vivo exposure and concluding with relapse-prevention planning. Outcome measures and self-report indicated substantial reductions in anxiety and health-related worry, alongside achievement of all functional goals. Improvements were maintained at 10- and 22-month follow-up, with low anxiety scores and marked reductions in beliefs about harm from previously feared stimuli. This case illustrates how a specific-phobia formulation and phobia-focussed CBT may be applicable to some MCS presentations following appropriate medical evaluation. It also highlights a potential role for clinical psychologists in respiratory settings. As a single case, the findings provide descriptive evidence of improvement but cannot establish a causal treatment effect.

Indexed as

Cognitive behavioural therapyExposure therapyIdiopathic environmental intoleranceMultiple chemical sensitivityOlder adultsSpecific phobia

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.