Evidence map›Paper›PMID 42663566›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2026

Unequal embodiment: racial and ethnic heterogeneity in the predictors and age-related health outcomes associated with accelerated biological aging.

Mariela Villalba Madrid, Francisco Ríos Casas, Mateo P Farina

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Mariela Villalba MadridDepartment of Human Development and Family Sciences, The University of Texas at Austin, Austin, Texas, United States.ORCID 0009-0008-2146-162X
Francisco Ríos CasasDepartment of Sociology, The University of Texas at Austin, Austin, Texas, United States.ORCID 0000-0002-8302-0132
Mateo P FarinaDepartment of Human Development and Family Sciences, The University of Texas at Austin, Austin, Texas, United States.ORCID 0000-0002-0765-6550

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Training Program in Population StudiesT32HD007081 · NICHD · UNIVERSITY OF TEXAS AUSTIN · PI Aprile Dawn Benner, Abigail Mae Weitzman · 1985 to 2026
$6.8M
Program Development and Pilot CoreP30AG066614 · NIA · UNIVERSITY OF TEXAS AT AUSTIN · PI DEBRA J. UMBERSON · 2020 to 2026
$5.2M
Scientific & Technical CoreP2CHD042849 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI Elizabeth T. Gershoff · 2017 to 2026
$5.2M
NIA NIH HHS P30 AG066614NIA NIH HHS P30AG066614NIA NIH HHS U01 AG009740NICHD NIH HHS P2C HD042849NICHD NIH HHS T32 HD007081
6 · The paper itself

Abstract

backgroundThis study investigates whether life-course and socioeconomic exposures are similarly associated with accelerated biological aging across racial and ethnic groups and whether accelerated biological aging predicts health outcomes equivalently across groups.

methodsData came from the Health and Retirement Study (2016-2022). Accelerated biological age was derived from 22 blood-based biomarkers from the 2016 Venous Blood Study. We used linear regression models with interactions between race/ethnicity and life-course exposures (childhood adversity and adult/midlife socioeconomic status (SES)) to assess group differences in accelerated aging. We used linear, ordered logistic, and logistic regression models with interactions between accelerated biological age and race/ethnicity to assess group differences in health outcomes. We examined differences by foreign-born status among Hispanic adults.

resultsAssociations between life-course exposures, accelerated biological aging, and health varied by race/ethnicity. Compared to non-Hispanic White adults, childhood health and adversity were not associated with accelerated biological aging for non-Hispanic Black and Hispanic adults, and among these groups, higher midlife SES did not decelerate biological aging. The association between accelerated biological age and health outcomes varied by race/ethnicity; accelerated biological age was less predictive among non-Hispanic Black and Hispanic adults. Among Hispanic adults, increased biological age was more strongly linked to multimorbidity among foreign-born individuals than U.S.-born individuals.

conclusionsThe processes linking life-course conditions to biological aging and biological aging to later-life health do not translate uniformly across racial/ethnic groups. Future research should explore the sources of heterogeneity in life-course exposures and the mechanisms by which biological age translates into health outcomes.

Indexed as

AgingEthnicityAgedBiomarkersBlack or African AmericanFemaleHispanic or LatinoHumansMaleMiddle AgedSocioeconomic Disparities in HealthUnited StatesWhiteBiomarkersCumulative biological riskLife-course epidemiologyMortalityMultimorbidity

Identifiers

PMID42663566
PMCPMC13529312

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.