Evidence map›Paper›PMID 42663464›Full record

ArticlemSystems2026

Spatial constraints determine the spread of plasmid-encoded antibiotic resistance between bacterial colonies.

Josep Ramoneda, Deepthi P Vinod, Yinyin Ma, Chujin Ruan, Julian Schmidt, Michael Manhart, Daniel C Angst, David R Johnson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Josep RamonedaDepartment of Environmental Microbiology, Swiss Federal Institute of Aquatic Science and Technology (Eawag), Dübendorf, Switzerland.ORCID 0000-0002-1806-2889
Deepthi P VinodDepartment of Environmental Microbiology, Swiss Federal Institute of Aquatic Science and Technology (Eawag), Dübendorf, Switzerland.
Yinyin MaDepartment of Environmental Microbiology, Swiss Federal Institute of Aquatic Science and Technology (Eawag), Dübendorf, Switzerland.
Chujin RuanDepartment of Environmental Microbiology, Swiss Federal Institute of Aquatic Science and Technology (Eawag), Dübendorf, Switzerland.
Julian SchmidtDepartment of Environmental Microbiology, Swiss Federal Institute of Aquatic Science and Technology (Eawag), Dübendorf, Switzerland.
Michael ManhartDepartment of Environmental Systems Science, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland.
Daniel C AngstDepartment of Environmental Systems Science, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland.ORCID 0000-0002-6512-4595
David R JohnsonDepartment of Environmental Microbiology, Swiss Federal Institute of Aquatic Science and Technology (Eawag), Dübendorf, Switzerland.ORCID 0000-0002-6728-8462

Funding

Agencia Estatal de Investigación PID2023-151209NA-I00Generalitat de Catalunya 2022-BP-00050Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 31003A_176101, 310030_207471Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung P2EZP3_199849Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PZ00P3_180147
6 · The paper itself

Abstract

Plasmid transfer among bacteria is an important driver of the spread of antibiotic resistance. Surface-associated bacterial biomass is a hotspot for plasmid transfer due to the dense spatial packing of cells, but this biomass is often sparse (composed of discrete bacterial colonies). Compared to plasmid dynamics within a single colony, the determinants of plasmid transfer between discrete colonies are less understood. Yet, colonies routinely physically collide with each other as they grow and expand across surfaces. Here, we experimentally demonstrate that collisions between colonies of

Indexed as

Drug Resistance, BacterialDrug Resistance, MicrobialEscherichia coliPlasmidsPseudomonas stutzeriAnti-Bacterial AgentsGene Transfer, HorizontalAnti-Bacterial Agentsantibiotic resistancebiofilmshorizontal gene transferindividual-based modellingmicrobial interactionsplasmid dynamicsspatial self-organization

Identifiers

PMID42663464
PMCPMC13595988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.