ArticleCureus2026
Adrenal Suppression From Mucosal Absorption of Dexamethasone Mouthwash.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present an unusual cause of reversible secondary adrenal insufficiency in a breast cancer patient receiving immunotherapy: systemic absorption of a dexamethasone mouthwash used to "swish and spit," without being swallowed, which resulted in elevated serum dexamethasone concentrations. Most such patients are presumed to have permanent adrenal insufficiency - well recognized as a complication of immunotherapy - and committed to life-long exogenous glucocorticoid treatment. Recognition of the potential for such oral mucosal steroids to be systemically absorbed, which might be more common than recognized, is critical for the avoidance of inappropriate management in immunotherapy patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.