Evidence map›Paper›PMID 42662932›Full record

ArticleOpen forum infectious diseases2026

Fatal Echovirus 11 Hepatitis in an Immunocompromised Adult Associated With Lineage 1.

Tom J Harryvan, Bettina C Geertsema-Hoeve, Wouter L Smit, Charlotte Schimmel, Katja C Wolthers, Miangela M Laclé, Vera Kemp, Kimberley S M Benschop, Bart J M Vlaminckx, Maarten Limper

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tom J HarryvanDepartment of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-0386-8302
Bettina C Geertsema-HoeveDepartment of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Wouter L SmitDepartment of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Charlotte SchimmelDepartment of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Katja C WolthersOrganoVIR Labs, Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam and Amsterdam Institute for Infection and Immunity, Amsterdam, The Netherlands.
Miangela M LacléDepartment of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.
Vera KempDepartment of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Kimberley S M BenschopCentre for Infectious Disease Control (CIb), Centre for Infectious Disease Research, Diagnostics and laboratory Surveillance (IDS), National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Bart J M VlaminckxDepartment of Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Maarten LimperDepartment of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2022-2023 European outbreak of severe neonatal hepatitis caused by echovirus 11 (E11) lineage 1 highlighted its pathogenic potential. We describe a fatal, recurrent hepatitis in an immunocompromised adult after B-cell depletion. Sequencing showed E11 lineage 1 infection. E11 lineage 1 should be considered in immunocompromised adults with unexplained hepatitis.

Indexed as

E11echovirus 11Enterovirushepatitislineage 1

Identifiers

PMID42662932
PMCPMC13521110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.