ArticleiScience2026
Comparative proteomic analysis of the composition of dECM and dECM-based inks compared to native tissues.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Advances in Decellularization of Fish Wastes for Extracellular Matrix Extraction in Sustainable Tissue Engineering and Regenerative Medicine.Bioengineering (Basel, Switzerland) · 2026Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regenerative medicine and tissue engineering approaches based on decellularized extracellular matrix (dECM) present the advantage of a relatively biomolecule-rich matrix that directs cell function in a tissue-specific manner. To evaluate compositional changes during standard ink processing, six porcine tissues (artery, breast, dermis, epidermis, muscle, and nerve) were independently decellularized and formulated into biocompatible inks, tracking matrisome complexity via comparative liquid chromatography-tandem mass spectrometry (LC-MS/MS). Results revealed a core matrisome found overlapping in all decellularized tissues, alongside tissue-specific components correlating with predicted functional definitions. Although the proportion of collagens (mostly the α1 chains of collagen type I and III) increased in the final inks, a median of 55 matrisomal proteins was detected. This complexity is far superior to non-dECM-based inks in terms of mimicking native tissues. Our results support the use of dECM-based inks and biomaterials in mimicking native tissue ECM complexity, demonstrating tissue-specific composition, which can improve future therapeutic approximations.
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Registered trials
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