Evidence map›Paper›PMID 42662859›Full record

ArticleFood chemistry: X2026

From waste to wellness: pomelo peel derived exosome-like nanoparticles reshape gut microbiota and enhance beneficial metabolites.

Liyi Li, Chaofan Chen, Tiantian Yang, Ran Tuo, Yingjie Huang, Xiaodan Zhao, Le Chu, Fatao He, Ping Li, Mingdong Lu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liyi LiDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325035, China.
Chaofan ChenCollege of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.
Tiantian YangCollege of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.
Ran TuoCollege of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.
Yingjie HuangCollege of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.
Xiaodan ZhaoCollege of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.
Le ChuJinan Fruit Research Institute, All China Federation of Supply and Marketing Cooperatives, Jinan 250014, China.
Fatao HeJinan Fruit Research Institute, All China Federation of Supply and Marketing Cooperatives, Jinan 250014, China.
Ping LiCollege of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.
Mingdong LuDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325035, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pomelo processing by-products, traditionally regarded as agricultural waste, are underutilized bioactive-rich candidate feedstocks for circular economy. This study optimized isolation protocol (differential centrifugation with PEG precipitation) for Pomelo Peel Exosome-Like Nanoparticles (PPELNs), uniform nanovesicles (195.8 ± 78.6 nm) with gastrointestinal stability. Proteomic analysis identified 1145 proteins enriched in carbohydrate, energy, amino-acid metabolism and stimulus response. In vitro human fecal fermentation model demonstrated PPELNs intervention altered gut microbiota, increased beneficial taxa (

Indexed as

Fecal slurry fermentationGut microbiotaMetabolomicsPPELNs

Identifiers

PMID42662859
PMCPMC13521061

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.