Evidence map›Paper›PMID 42662827›Full record

ArticleSynthetic and systems biotechnology2027

Combinatorial metabolic engineering of

Liyang Xu, Chuxian Peng, Wenjing Pan, Yingjia Tong, Jinsong Shi, Zhenghong Xu, Hui Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liyang XuSchool of Life Sciences and Health Engineering, Jiangnan University, Wuxi, 214122, China.
Chuxian PengSchool of Life Sciences and Health Engineering, Jiangnan University, Wuxi, 214122, China.
Wenjing PanSchool of Life Sciences and Health Engineering, Jiangnan University, Wuxi, 214122, China.
Yingjia TongSchool of Life Sciences and Health Engineering, Jiangnan University, Wuxi, 214122, China.
Jinsong ShiSchool of Life Sciences and Health Engineering, Jiangnan University, Wuxi, 214122, China.
Zhenghong XuCollege of Biomass Science and Engineering, Sichuan University, Chengdu, 610065, China.
Hui LiSchool of Life Sciences and Health Engineering, Jiangnan University, Wuxi, 214122, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Androstenedione (AD) is an important precursor for the synthesis of corticosteroids, sex hormones, and other high-value steroid pharmaceuticals. Microbial conversion of phytosterols provides a sustainable route for AD production, but current production levels remain insufficient for practical industrial application. In this study, a modular metabolic engineering strategy was developed to improve AD biosynthesis from phytosterols in

Indexed as

AndrostenedioneMetabolic engineeringMycobacterium neoaurumPhytosterols

Identifiers

PMID42662827
PMCPMC13520905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.