ArticleACS omega2026
Analytical Methodology for Sensitive Detection of the Antidepressant Drug Duloxetine in Urine Samples Using Riboflavin-Coated Fe
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Antidepressant drugs are widely used and effective in treating mood disorders. Monitoring low concentrations of these drugs in biological samples such as solid tissues and biofluids with high sensitivity is challenging for conventional analysis methods. The present study aims to determine duloxetine molecules at trace levels in urine samples by using a simple sample preparation method and a high-performance liquid chromatography coupled with diode array detection (HPLC-DAD) system. This study presents the development of a novel separation and preconcentration method for the trace-level determination of duloxetine using HPLC-DAD following magnetic solid-phase extraction (MSPE). For this purpose, tetraethyl orthosilicate (TEOS)-coated magnetic nanoparticles functionalized with riboflavin (Fe
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