Evidence map›Paper›PMID 42662730›Full record

ArticleACS omega2026

Drug Repositioning for Multiresistant

Daniela S Gonçalves, Nagela B S Silva, Anna L O Santos, Sara L de Souza, Gabriel G Calefi, Ralciane de P Menezes, Andreia M de Oliveira, Ghabriel Honório-Silva, Camila M de Andrade, Marcos P O Almeida and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Daniela S GonçalvesLaboratory of Antimicrobial Testing, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.
Nagela B S SilvaLaboratory of Antimicrobial Testing, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.
Anna L O SantosLaboratory of Antimicrobial Testing, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.
Sara L de SouzaLaboratory of Antimicrobial Testing, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.
Gabriel G CalefiLaboratory of Antimicrobial Testing, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.
Ralciane de P MenezesLaboratory of Antimicrobial Testing, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.
Andreia M de OliveiraLaboratory of Antimicrobial Testing, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.
Ghabriel Honório-SilvaInnovation Center in Salivary Diagnostic and Nanobiotechnology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.
Camila M de AndradeInnovation Center in Salivary Diagnostic and Nanobiotechnology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.
Marcos P O AlmeidaLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.ORCID https://orcid.org/0000-0003-3835-1925
Thales A M FernandesLaboratory of Applied Toxinology, Butantan Institute, São Paulo 05503-900, Brazil.
Bellisa de F BarbosaLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.ORCID https://orcid.org/0000-0003-4611-2844
Eloísa A V FerroLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.
Robinson Sabino-SilvaInnovation Center in Salivary Diagnostic and Nanobiotechnology, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.
Carlos H G MartinsLaboratory of Antimicrobial Testing, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Minas Gerais 38400-694, Brazil.ORCID https://orcid.org/0000-0001-8634-6878

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phenomenon of antimicrobial resistance (AMR) can occur naturally through spontaneous mutation without major damage; however, the overuse and misuse of antimicrobials is responsible for millions of deaths annually. The development of new drugs is an expensive and slow process, while repositioning active substances to different biological activities is a cheaper and faster option. The aim of this study was to evaluate the possibility of repositioning 640 known chemical compounds provided by the Medicines for Malaria Venture organization for antibacterial and antibiofilm activities against multidrug-resistant

Identifiers

PMID42662730
PMCPMC13520533

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.