Evidence map›Paper›PMID 42662722›Full record

ReviewFrontiers in endocrinology2026

Bone marrow adipoq-lineage cells in regulating the bone and marrow microenvironment: identities, functions, and mechanisms.

Chunyan Zhang, Xiaohui Gu, Yuyan Xiang, Chanchan Zheng, Lei Yang, Jianquan Chen

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chunyan Zhang *Department of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China.
Xiaohui Gu *Center for Rehabilitation Medicine, Department of Orthopedics, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China.
Yuyan Xiang *Department of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China.
Chanchan ZhengDepartment of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China.
Lei YangCenter for Health Sciences and Engineering (CHSE), Hebei Key Laboratory of Biomaterials and Smart Theranostics, School of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin, China.
Jianquan ChenDepartment of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone marrow Adipoq-lineage cells refer to all cells that have ever expressed Adipoq (Adiponectin) and their progeny. They contribute not only to marrow adipogenesis but also to osteoclast regulation, hematopoietic support, vascular maintenance, and post-injury regeneration. Recent single-cell transcriptomic and genetic fate-mapping studies have revealed unexpected heterogeneity within this lineage, such as genuine adipogenic precursors (MALPs), bipotent adipo-osteoprogenitors (Adipoq

Indexed as

AdiponectinBone and BonesBone MarrowBone Marrow CellsCell LineageCellular MicroenvironmentAnimalsCell DifferentiationHematopoiesisHumansOsteogenesisAdiponectinadipo-lineage progenitorsadipo-osteoprogenitorsadipoq-lineage cellsbone marrow nichehematopoiesisosteoclastogenesisskeletal stem and progenitor cells

Identifiers

PMID42662722
PMCPMC13520346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.