Evidence map›Paper›PMID 42662717›Full record

ArticleACS omega2026

Development and Biological Evaluation of FL18-Based Novel Antimicrobial Peptide Constructs Against Bacterial Pathogens.

Neslihan Zencirci, Büşra Kılıç, Öznur Akbal Vural, Gözde Koşarsoy Ağçeli, Cagatay Karaaslan, Ömür Çelikbıçak

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Neslihan ZencirciGraduate School of Science and Engineering, Polymer Science and Technology Division, Hacettepe University, Ankara 06800, Turkey.ORCID https://orcid.org/0009-0008-4447-7026
Büşra KılıçFaculty of Science, Department of Biology, Molecular Biology Section, Hacettepe University, Ankara 06800, Turkey.ORCID https://orcid.org/0000-0003-4299-1060
Öznur Akbal VuralAdvanced Technologies Application and Research Center, Hacettepe University, Ankara 06800, Turkey.ORCID https://orcid.org/0000-0003-1972-5987
Gözde Koşarsoy AğçeliFaculty of Science, Department of Biology, Biotechnology Division, Hacettepe University, Ankara 06800, Turkey.ORCID https://orcid.org/0000-0001-8318-8990
Cagatay KaraaslanFaculty of Science, Department of Biology, Molecular Biology Section, Hacettepe University, Ankara 06800, Turkey.ORCID https://orcid.org/0000-0003-4857-0857
Ömür ÇelikbıçakFaculty of Science, Department of Chemistry, Physical Chemistry Division, Hacettepe University, Ankara 06800, Turkey.ORCID https://orcid.org/0000-0003-2683-0312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance has become a serious global health challenge, increasing the need for new therapeutic strategies beyond conventional antibiotics. In this study, FL18 and its chimeric derivatives, FL18-TAT8 and FL18-Ahx-TAT8, were designed to combine antimicrobial activity with the cell-associated advantages of a cell-penetrating peptide motif and were synthesized by Fmoc-based solid-phase peptide synthesis. Their molecular masses were confirmed by MALDI-MS analysis. The antibacterial activities of the peptides were evaluated against representative Gram-negative and Gram-positive bacterial strains, including

Identifiers

PMID42662717
PMCPMC13520428

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.