Evidence map›Paper›PMID 42662610›Full record

ArticleResearch and practice in thrombosis and haemostasis2026

Navigating the pause-patient experiences with perioperative anticoagulation interruption: a qualitative study.

Alfonso Tafur, Sally Jensen, Albert Marquez, Steven Greenberg, Barry Wallach, Jean Connors, Jerrold Levy, Marisa Durante, Alexis Preston, James Douketis

Abstract read
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Article in Research and practice in thrombosis and haemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Alfonso TafurVascular Medicine, Endeavor Health, Evanston, Illinois, USA.
Sally JensenResearch Institute, Endeavor Health, Evanston, Illinois, USA.
Albert MarquezMayo Clinic, Rochester, Minnesota, USA.
Steven GreenbergDepartment of Anesthesia, Endeavor Health, Evanston, Illinois, USA.
Barry WallachPatient Representative, Illinois, USA.
Jean ConnorsBrigham and Women's Hospital, Boston, Massachusetts, USA.
Jerrold LevyDuke University Medical Center, Durham, North Carolina, USA.
Marisa DuranteCardiovascular Institute, Endeavor Health, Evanston, Illinois, USA.
Alexis PrestonCardiovascular Institute, Endeavor Health, Evanston, Illinois, USA.
James DouketisSt. Joseph's Healthcare Hamilton, McMaster University, Hamilton, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients on chronic anticoagulation frequently undergo temporary medication interruption for surgical or invasive procedures, yet the patient perspective on this experience remains poorly characterized. Objectives: The aim of this study was to identify the concerns, preferences, and unmet needs of patients undergoing perioperative anticoagulation interruption to inform patient-centered care strategies. Methods: A qualitative study using 7 semistructured focus groups was conducted between 2022 and 2023 at a single academic health system. Twenty-two adults on chronic oral anticoagulation who had recently undergone planned interruption for high-risk procedures were enrolled. Groups were stratified by anticoagulant type (warfarin vs direct oral anticoagulant [DOAC]). Emergent themes from focus group transcripts were identified using grounded theory with iterative open coding and consensus analysis via Dedoose software. Results: Nineteen themes were identified and consolidated into 5 core categories: (1) Risk Perception, reflecting fears of bleeding and clotting shaped by personal history; (2) Communication and Instruction Clarity, emphasizing the need for clear, timely guidance; (3) Self-Management and Logistical Challenges, including difficulties with injections, medication tracking, and dietary management; (4) Healthcare System Gaps, including care coordination failures and access delays; and (5) Emotional and Adaptive Responses, including stress and creative coping strategies. Bruising and injection challenges were more prominent concerns than major clinical events. Conclusion: Perioperative anticoagulation interruption poses substantial informational, emotional, and logistical burdens on patients. Enhancing communication, supporting self-management, and improving system coordination are essential components of anticoagulation stewardship. Integration of patient-reported outcomes into future trials is warranted.

Indexed as

AnticoagulantsPerioperative CareWarfarinAdministration, OralAdultAgedFemaleFocus GroupsHemorrhageHumansMaleMiddle AgedPatient-Centered CareQualitative ResearchTreatment InterruptionAnticoagulantsWarfarinanticoagulantsfocus groupspatient experienceperioperative carequalitative research

Identifiers

PMID42662610
PMCPMC13521166

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.