Evidence map›Paper›PMID 42662601›Full record

ArticleFrontiers in immunology2026

Spatial and temporal immune landscapes of non-necrotic granulomas in two murine tuberculosis models with divergent disease outcomes.

Malik Zohaib Ali, Taru S Dutt, Johnathan Patterson, Angela Minic, Kimberly R Jordan, Sara E Maloney Norcross, Bernd Meibohm, Mercedes Gonzalez-Juarrero

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Malik Zohaib AliMycobacteria Research Laboratories, Colorado State University, Fort Collins, CO, United States.
Taru S DuttDepartment of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, CO, United States.
Johnathan PattersonMycobacteria Research Laboratories, Colorado State University, Fort Collins, CO, United States.
Angela MinicDepartment of Immunology and Microbiology , University of Colorado Anschutz Medical Campus, Denver, CO, United States.
Kimberly R JordanDepartment of Immunology and Microbiology , University of Colorado Anschutz Medical Campus, Denver, CO, United States.
Sara E Maloney NorcrossEngineering and Advanced Technology Department, RTI International, Durham, NC, United States.
Bernd MeibohmDepartment of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, United States.
Mercedes Gonzalez-JuarreroMycobacteria Research Laboratories, Colorado State University, Fort Collins, CO, United States.

Funding

Aerosol spectinamide-1599 therapy against tuberculosisR01AI120670 · NIAID · COLORADO STATE UNIVERSITY · PI BRAUNSTEIN, MIRIAM S., GONZALEZ-JUARRERO, MERCEDES · 2016 to 2020
$3.6M
Inhalational therapy with spectinamides within new regimens of TB therapyR01AI178885 · NIAID · COLORADO STATE UNIVERSITY · PI Mercedes Gonzalez-Juarrero, BERND MEIBOHM · 2024 to 2026
$2.4M
Vectra Polaris microscope imaging systemS10OD030263 · OD · COLORADO STATE UNIVERSITY · PI GONZALEZ-JUARRERO, MERCEDES · 2021 to 2021
$452k
NIAID NIH HHS R01 AI120670NIAID NIH HHS R01 AI178885NIH HHS S10 OD030263
6 · The paper itself

Abstract

Tuberculosis (TB), caused by

Indexed as

GranulomaMycobacterium tuberculosisTuberculosisAnimalsBacterial LoadDisease Models, AnimalDisease ProgressionFemaleLungMacrophagesMiceMice, Inbred BALB CMice, Inbred C3HBALB/c mouse modelC3HeB/FeJ mouse modelimmune cellsinForm Tissue Findermultiplex fluorescence immunohistochemistryMycobacterium tuberculosisnon-necrotic granulomaspatial analysis

Identifiers

PMID42662601
PMCPMC13519991

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.