ArticleACS omega2026
Tumor-Selective Vascular Modulation by Acid-Cleavable Retro-Inverso Bradykinin Conjugates Enhances the Antitumor Efficacy of Nanomedicine.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
7 authors.
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Abstract
Enhancing the tumor accumulation of nanomedicines through vascular modulation represents a promising strategy to improve anticancer drug delivery. Bradykinin (BK), a potent vasoactive peptide, can enhance intratumoral blood flow and vascular permeability; however, its clinical application is hampered by rapid proteolytic degradation and systemic side effects, including hypotension. To address these limitations, we developed P-RIBKs,
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