ArticleOpen forum infectious diseases2026
Incidence, Persistence, and Clearance of Anal Human Papillomavirus Infections Among Adolescent and Young Men Who Have Sex With Men in China: An Observational Cohort Study.
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: High-risk adolescent and young men who have sex with men (MSM) populations in China experience a significant burden of human papillomavirus (HPV) infections, particularly involving HPV6, HPV11, HPV16, and HPV18. This prospective observational study investigated the prevalence, persistence, and clearance of HPV, highlighting the critical need for targeted interventions. Methods: Adolescent and young MSM across 4 Chinese provinces participated in the UniTest Study. Anal swab samples were collected at baseline and follow-up for HPV detection and genotyping. Sociodemographic and behavioral data were obtained through self-administered questionnaires. Incidence, persistence, and clearance rates were calculated, and potential determinants were analyzed using Poisson regression models. Results: The overall incidence of any HPV genotype was 42.1 per 1000 person-months (pm), with HPV16 (5.6/1000 pm), HPV6 (4.1/1000 pm), and HPV58 (3.2/1000 pm) being the most common incident genotypes. Persistent infections were observed in 28.0%, with HPV11 (4.5%), HPV6 (4.0%), and HPV16 (3.5%) as the top persistent genotypes. The clearance rate for any HPV genotype was 102.6 per 1000 pm. Participants who sought sex partners online had a higher likelihood of HPV incidence (risk ratio [RR] = 1.543, 95% confidence interval [CI] 1.043-2.282), while those with above-average academic performance had a lower likelihood of HPV incidence (RR = 1.551, 95% CI 1.058-2.274). Compared with Han, other ethnicities were associated with increased HPV clearance (RR = 5.757, 95% CI 1.067-31.067). Conclusions: This study uncovers a substantial incidence of HPV infections among adolescent and young MSM in China, underscoring the imperative for focused health education and the swift implementation of customized HPV vaccination initiatives. Through the prioritization of preventive strategies and vaccination campaigns, it's possible to significantly diminish the impact of HPV infections and enhance sexual health outcomes within this at-risk group.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.