ArticleBioinformation2026
Polymerized injectable platelet-rich fibrin with octacalcium phosphate (bontree®) for treatment of periodontal intrabony defects assessed using CBCT: A randomized controlled clinical trial.
Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Periodontal intrabony defects remain a significant clinical challenge due to the difficulty in achieving predictable regeneration of lost alveolar bone. Therefore, it is of interest to evaluate the effectiveness of injectable platelet-rich fibrin (I-PRF) polymerized with octacalcium phosphate (OCP) compared to OCP alone in treating intrabony defects using a split-mouth design. Hence, twelve patients with chronic periodontitis contributed twenty-four sites, assessed clinically and radiographically using CBCT at baseline and six months. Both groups demonstrated significant improvements in clinical and radiographic parameters, with greater percentage changes observed in the I-PRF + OCP group, although intergroup differences were not statistically significant. The adjunctive use of polymerized I-PRF with OCP shows a favorable trend in enhancing periodontal regeneration and warrants further investigation in larger studies.
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