ArticleTherapeutic radiology and oncology2023
Total scalp irradiation using pencil beam scanning proton therapy for dermatofibrosarcoma protuberans: case study and photon dosimetric comparison-a case report.
Article in Therapeutic radiology and oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Background: This report describes a patient with extensive dermatofibrosarcoma protuberans of the scalp treated with a technically challenging total scalp irradiation (TSI) plan using intensity-modulated proton therapy (IMPT). Case Description: A 33-year-old female presented with a rapidly progressive extensive scalp lesion status post wide local excision with rotational flap reconstruction. Pathology identified diffuse positive margins and high-risk features. A 4-field multi-field-optimized IMPT plan was generated and planned to deliver 6,000 cGy in 30 fractions robustly optimized using 3 mm setup and 3.5% range uncertainty. A volumetric-modulated arc radiotherapy (VMAT) plan matched for target coverage was generated for comparison purposes. The patient successfully completed treatment and remains without evidence of disease at 9 months. IMPT achieved acceptable target coverage with adequate dose homogeneity and robustness. Optimal treatment planning utilized noncoplanar fields, overlapping field dose gradients, and Monte Carlo dose calculations. Organs at risks (OARs) doses with IMPT were significantly reduced compared to VMAT, particularly for the normal brain, hippocampus, pituitary gland, cochlea, and optic structures. Conclusions: TSI using IMPT is dosimetrically favorable with unique technical considerations. It achieves dramatic dose sparing to critical OARs compared to modern photon techniques and should be considered when irradiation of an extensive scalp volume is indicated to reduce the long-term toxicity risk of unintentional integral dose.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.