Evidence map›Paper›PMID 42662192›Full record

ArticleACS omega2026

Role of Amyloid Fibrils in Enhancing the Protective Properties of Microbial Melanin against Oxidative Stress, UV Damage, and AGE-Related Cytotoxicity in Human Keratinocytes.

Shana Perrella, Talayeh Kordjazi, Maria Liccardo, Loredana Mariniello, Ivana Sirangelo, Odile Francesca Restaino, Clara Iannuzzi

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shana PerrellaDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy.
Talayeh KordjaziDepartment of Chemical Sciences, University of Naples Federico II, Monte Sant'Angelo Campus, Via Cintia 4, 80126 Naples, Italy.
Maria LiccardoDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy.
Loredana MarinielloDepartment of Chemical Sciences, University of Naples Federico II, Monte Sant'Angelo Campus, Via Cintia 4, 80126 Naples, Italy.ORCID https://orcid.org/0000-0002-6800-5890
Ivana SirangeloDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy.
Odile Francesca RestainoDepartment of Chemical Sciences, University of Naples Federico II, Monte Sant'Angelo Campus, Via Cintia 4, 80126 Naples, Italy.ORCID https://orcid.org/0009-0002-9617-9166
Clara IannuzziDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biological properties of microbial melanins, whose structures resemble those of animal-derived eumelanin pigments, have been poorly investigated in mammalian cell systems, as well as the role of amyloid fibrils in modulating melanin activities. Indeed, although amyloid fibrils are known to be crucial in the melanogenesis process, their functional role is not fully understood. In this study, we have investigated, for the first time, the ability of a microbial eumelanin, biotechnologically produced and purified by

Identifiers

PMID42662192
PMCPMC13520022

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.