Evidence map›Paper›PMID 42662162›Full record

ArticleACS omega2026

Development of Oral pH-Sensitive Eudragit L100-Functionalized

Bui Thi Phuong Thuy, Phuong T M Ha, Ngoc Yen Nguyen, Nguyen Trong Tuan, Huynh Vu Thanh Luong, Quyen Thi Bich Tran, Trieu Phu Hau, Duy Toan Pham

Abstract read
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In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bui Thi Phuong ThuyFaculty of Basic Sciences, Van Lang University, Ho Chi Minh City 70000, Vietnam.ORCID https://orcid.org/0000-0001-5487-414X
Phuong T M HaFaculty of Pharmacy and Nursing, Tay Do University, 68 Tran Chien Street, Thanh My Area Cai Rang Ward, Can Tho 94000, Vietnam.
Ngoc Yen NguyenFaculty of Health Sciences, College of Natural Sciences, Can Tho University, Can Tho 94000, Vietnam.
Nguyen Trong TuanFaculty of Health Sciences, College of Natural Sciences, Can Tho University, Can Tho 94000, Vietnam.
Huynh Vu Thanh LuongFaculty of Chemical Engineering, College of Engineering, Can Tho University, Can Tho 94000, Vietnam.
Quyen Thi Bich TranFaculty of Chemical Engineering, College of Engineering, Can Tho University, Can Tho 94000, Vietnam.ORCID https://orcid.org/0000-0002-9304-5544
Trieu Phu HauFaculty of Health Sciences, College of Natural Sciences, Can Tho University, Can Tho 94000, Vietnam.
Duy Toan PhamFaculty of Health Sciences, College of Natural Sciences, Can Tho University, Can Tho 94000, Vietnam.ORCID https://orcid.org/0000-0002-8693-3367

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amphotericin B (AmB) is a poorly water-soluble drug with low oral bioavailability and high nephrotoxicity. Thus, this study developed oral AmB-loaded pH-sensitive Eudragit L100-functionalized silk fibroin nanoparticles (SF/EL-AmB) to enhance its oral bioavailability and reduce its renal toxicity. The particles were formulated using two different methods of desolvation and adsorption, followed by thorough characterizations regarding particle size, polydispersity index, zeta potential, chemical interactions, AmB entrapment efficiency, specific surface area, drug release in simulated oral conditions, and

Identifiers

PMID42662162
PMCPMC13519923

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.