Evidence map›Paper›PMID 42662127›Full record

ArticleFrontiers in dementia2026

Diagnostic and treatment strategies in a memory clinic for older adults in a region with a predominantly low-income population.

Patricia Solis, Ines Mintz, Nancy Medel, Zulma Sevillano, Julieta Lisso, Nicolas Irureta, Mauricio Federico Zalazar-Jaime, Brenda Giagante, Maria Carolina Dalmasso, Silvia Kochen

Abstract read
In one paragraph

Article in Frontiers in dementia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Patricia SolisStudies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce), Florencio Varela, Argentina.
Ines MintzStudies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce), Florencio Varela, Argentina.
Nancy MedelStudies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce), Florencio Varela, Argentina.
Zulma SevillanoStudies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce), Florencio Varela, Argentina.
Julieta LissoStudies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce), Florencio Varela, Argentina.
Nicolas IruretaStudies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce), Florencio Varela, Argentina.
Mauricio Federico Zalazar-JaimeFacultad de Psicología, Universidad Nacional de Córdoba, Córdoba, Argentina.
Brenda GiaganteStudies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce), Florencio Varela, Argentina.
Maria Carolina DalmassoStudies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce), Florencio Varela, Argentina.
Silvia KochenStudies in Neuroscience and Complex Systems Unit (ENyS-CONICET-Universidad Nacional Arturo Jauretche-Hospital El Cruce), Florencio Varela, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early detection and interdisciplinary management of cognitive impairment are essential, particularly in socioeconomically vulnerable populations with limited access to specialized care. To address this need, a Memory Clinic was established in 2016 within the Argentine public healthcare system in Florencio Varela. This region reflects a condition of structural poverty, where 16.2% of the population lives in poverty according to Unsatisfied Basic Needs (UBN) and over 60% of residents lack essential services. Methods: The study included 1,204 individuals (852 women, 353 men) with a mean age of 72 years and 6 years of education, most of whom attended through self-motivation based on memory complaints. Based on cumulative experience, a work protocol tailored to the local population was established, comprising a cognitive battery (MMSE, ACE-R, FAB, CDR, FAQ, Zarit Scale, NPI-Q), neurological and functional evaluation, laboratory testing, and neuroimaging. Diagnoses are determined by consensus in weekly interdisciplinary meetings. Additionally, a cognitive reserve questionnaire was culturally adapted, implemented, and tested in a subpopulation of 315 people. Over the past three years, the clinic also contributed to the formation of GeNED.ar (Genetics and Neuroimaging in Aging and Dementia in Argentina), a national cohort study. Results: Evaluated patients received a definitive diagnosis along with guidance on healthy aging and, when necessary, appropriate pharmacological treatment or cognitive stimulation therapy. The implementation of the adapted questionnaire revealed a significantly lower cognitive reserve in patients with dementia. Furthermore, active participation in research projects like GeNED.ar demonstrated enhancements in clinical care, supported staff training, and promoted alignment with international standards. Conclusion: As the only public healthcare center of its kind in the region, this Memory Clinic provides high-quality, research-integrated cognitive care to a vulnerable elderly population. This center offers a successful and replicable model for similar socioeconomic contexts across Latin America.

Indexed as

Argentinacognitive reservecognitive stimulation therapydementiaGeNED.arpublic healthvulnerable population

Identifiers

PMID42662127
PMCPMC13519976

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.