Evidence map›Paper›PMID 42662067›Full record

ArticleJournal of the Endocrine Society2026

Genetic screening and functional characterization of

Su-Hong Huang, Feng Sun, Fei Luo, Hui-Lan Li, Hai-Lin Huang, Jing-Min Guo, Chong Guo, Xue-Hua Zhang, Shuang-Xia Zhao, Bo-Kun Wei and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Endocrine Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Genetic screening and functional characterization ofJournal of the Endocrine Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Su-Hong HuangDepartment of Clinical Laboratory, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province 350014, China.
Feng SunDepartment of Endocrinology, The Core Laboratory in Medical Center of Clinical Research, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
Fei LuoDepartment of Clinical Laboratory, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province 350014, China.
Hui-Lan LiThe School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, Fujian Province 350004, China.
Hai-Lin HuangDepartment of Clinical Pathology, Shaowu Municipal Hospital, Shaowu, Fujian Province 354000, China.
Jing-Min GuoDepartment of Child Healthcare, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province 350001, China.
Chong GuoDepartment of Child Healthcare, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province 350001, China.
Xue-Hua ZhangDepartment of Ultrasound, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province 350014, China.
Shuang-Xia ZhaoDepartment of Endocrinology, The Core Laboratory in Medical Center of Clinical Research, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
Bo-Kun WeiThe School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, Fujian Province 350004, China.
Huai-Dong SongDepartment of Endocrinology, The Core Laboratory in Medical Center of Clinical Research, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.ORCID https://orcid.org/0000-0002-9609-5803
Rui LiDepartment of Endocrinology, The Core Laboratory in Medical Center of Clinical Research, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.ORCID https://orcid.org/0009-0000-0813-4335
Feng ChengDepartment of Clinical Laboratory, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province 350014, China.ORCID https://orcid.org/0009-0004-1333-383X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: Congenital hypothyroidism (CH) is the most prevalent endocrine disorders detected via newborn screening. Variants in dual oxidase 2 ( Objective: To characterize the genetic spectrum of Methods: We enrolled 184 Han Chinese CH patients. Results: Of the 184 patients, 114 (61.96%) carried genetic variants. Conclusion:

Indexed as

congenital hypothyroidismDUOX2enzymatic activitygenotype–phenotype analysis

Identifiers

PMID42662067
PMCPMC13519044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.