Evidence map›Paper›PMID 42662061›Full record

ArticleiMeta2026

Gut microbiota-mediated immune and metabolic dysregulation in coronary artery disease progression and prognosis.

Honghong Liu, Siqin Feng, Lifeng Liang, Muyun Tang, Yifei Wang, Yiyang Wang, Zhiyu Zhang, Haiping Xing, Chenhong Zhang, Ran Tian and 1 more

Abstract readLetter
In one paragraph

Article in iMeta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Honghong LiuDepartment of Internal Medicine, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Siqin FengDepartment of Internal Medicine, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Lifeng Liang01Life Institute Shenzhen China.
Muyun TangDepartment of Cardiology, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Yifei WangDepartment of Cardiology, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Yiyang WangDepartment of Cardiology, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Zhiyu ZhangDepartment of Cardiology, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Haiping XingDepartment of Internal Medicine, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Chenhong ZhangState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai China.ORCID https://orcid.org/0000-0002-4462-892X
Ran TianDepartment of Cardiology, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.ORCID https://orcid.org/0009-0003-2292-4247
Shuyang ZhangDepartment of Cardiology, Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.ORCID https://orcid.org/0000-0002-1532-0029

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota has emerged as a metabolically active endocrine-like organ with a crucial role in coronary artery disease (CAD), yet its contribution to adverse clinical outcomes remains incompletely understood. In this prospective cohort of 319 participants, we integrated metagenomic and metabolomic profiling with longitudinal follow-up over a median of 1.85 years. Fecal microbiota transplantation from patients with CAD transmitted susceptibility to atherosclerosis in antibiotic-treated

Identifiers

PMID42662061
PMCPMC13519092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.