Evidence map›Paper›PMID 42661956›Full record

ArticleSAGE open medical case reports2026

Rhabdomyolysis after strenuous exercise: A case report.

Rong-Rong Zhen, Yi-Fan Shen, Guan-Cheng Li, Ying-Jie Zhu, Li-Min Zhang, Ya-Nan Zhang, Qi Hong, Xin-Lu Wang, Chao Gu, Ting Shen and 1 more

Abstract readCase Reports
In one paragraph

Article in SAGE open medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rong-Rong ZhenDepartment of Emergency and Critical Care Medicine, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, China.ORCID https://orcid.org/0000-0002-5373-7765
Yi-Fan ShenDepartment of Emergency and Critical Care Medicine, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, China.
Guan-Cheng LiDepartment of Acupuncture and Moxibustion, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, China.
Ying-Jie ZhuDepartment of Colorectal, Wusong Hospital, Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
Li-Min ZhangDepartment of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, China.
Ya-Nan ZhangDepartment of Emergency and Critical Care Medicine, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, China.
Qi HongDepartment of Emergency and Critical Care Medicine, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, China.
Xin-Lu WangDepartment of Emergency and Critical Care Medicine, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, China.
Chao GuDepartment of Special Treatment, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, China.
Ting ShenDepartment of Medical Service, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, China.
Guo-Liang YanDepartment of Emergency and Critical Care Medicine, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhabdomyolysis is a syndrome characterized by necrosis and the disruption of striated muscle fibers. It is secondary to etiologies, such as trauma, ischemia, or toxin exposure. Rhabdomyolysis releases intracellular muscle constituents into systemic circulation, frequently leading to acute kidney injury. Clinical manifestations, including muscle weakness, myalgia, and dark urine, in young adults with nontraumatic etiologies are frequently underrecognized. Early diagnosis and prompt intervention are critical for mitigating complications. We report a case of a 27-year-old male who was admitted to Shanghai Municipal Hospital of Traditional Chinese Medicine in September 2024, presenting with exertional rhabdomyolysis complicated by acute kidney injury. Serum myoglobin (>12,000 ng/mL) and creatine kinase (210,000 U/L) were strikingly elevated. Therapeutic intervention consisted of vigorous fluid resuscitation, urinary alkalinization, electrolyte correction, and combined intermittent renal replacement therapy and hemoperfusion. The patient recovered uneventfully and was discharged in stable condition. It highlights the vulnerability of young individuals to rhabdomyolysis and underscores the seriousness of the condition. The adjunctive use of intermittent renal replacement therapy combined with hemoperfusion was observed to reduce circulating creatinine and myoglobin levels, which may serve as a reference for future therapeutic decision-making.

Indexed as

AKIcase reportIRRTrhabdomyolysisstrenuous exercise

Identifiers

PMID42661956
PMCPMC13519197

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.