Evidence map›Paper›PMID 42661885›Full record

ArticleFrontiers in medicine2026

Prenatal diagnosis and outcomes of fetal cardiac tumors: a 10-year single-center study of 81 cases.

Longzhuang Peng, Yangqing Zuo, Jinwen Chen, Zongjie Weng, Qiumei Wu, Qiong Huang, Wen Ling

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Longzhuang Peng *Department of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Yangqing Zuo *Department of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Jinwen Chen *Department of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Zongjie WengDepartment of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Qiumei WuDepartment of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Qiong HuangDepartment of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.
Wen LingDepartment of Medical Ultrasonics, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to comprehensively analyze the prenatal phenotype, genetic basis, and postnatal trajectory of a large cohort of fetuses with fetal cardiac tumors (FCTs). Methods: This retrospective study included 81 fetuses diagnosed with FCTs at our center between 2014 and 2024. We reviewed prenatal ultrasound and MRI findings, genetic testing results, and postnatal follow-up data, extending to a minimum follow-up period of 1 year. Tumor characteristics, complications, and predictors of tuberous sclerosis complex (TSC) and adverse outcomes were analyzed. Results: Among the 81 cases FCTs, cardiac rhabdomyoma (CR) was the most common tumor (66 cases, 81.5%), followed by fibroma ( Conclusion: Tumor multiplicity, rather than size, was more strongly associated with TSC in fetal CR. Ultrasound combined with MRI improved the prenatal detection rate of fetal TSC. In the absence of hemodynamic compromise and TSC, FCTs had a favorable prognosis. These findings support a management algorithm based on tumor type, multiplicity, tumor size/location, and genetic testing.

Indexed as

echocardiographyfetal cardiac tumorsprenatal diagnosisprognosistuberous sclerosis complex

Identifiers

PMID42661885
PMCPMC13518546

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