Evidence map›Paper›PMID 42661797›Full record

ArticleFrontiers in nutrition2026

Bridging the gap between biomarkers and bedside decisions: the prognostic value of the blood urea nitrogen-to-albumin ratio in sepsis-associated AKI.

Hongmin Chen, Xiaoxiao Qu, Xinxing Wang, Guosong Jiang, Zimiao Zhu

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Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Hongmin ChenDepartment of Clinical Laboratory, Wenzhou Longwan Hospital of Integrated Traditional Chinese and Western Medicine, Wenzhou, Zhejiang, China.
Xiaoxiao QuDepartment of Clinical Laboratory, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Xinxing WangDepartment of Clinical Laboratory, Chengdu BOE Hospital, Chengdu, Sichuan, China.
Guosong JiangDepartment of Pulmonary and Critical Care Medicine, The First People's Hospital of Zhaotong and Zhaotong Hospital Affiliated to Kunming Medical University, Zhaotong, Yunnan, China.
Zimiao ZhuDepartment of Clinical Laboratory, Central Blood Station of Wenzhou, Wenzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: While sepsis-associated acute kidney injury (AKI) is a leading cause of mortality in intensive care units, identifying high-risk patients remains clinically challenging. Traditional severity scores often fail to capture dynamic metabolic disturbances. This study aimed to characterize the association between the blood urea nitrogen-to-albumin ratio (BAR)-a novel biomarker reflecting systemic nitrogen metabolism and nutritional status-and 28-day mortality in patients with sepsis-associated AKI undergoing continuous renal replacement therapy (CRRT). Methods: This prospective observational study included 790 patients with sepsis-associated AKI undergoing CRRT. log Results: Multivariable analysis identified log Conclusions: log

Indexed as

28-day mortalityblood urea nitrogen-to-albumin ratio (BAR)continuous renal replacement therapy (CRRT)prognostic stratificationsepsis-associated AKIsubgroup analysis

Identifiers

PMID42661797
PMCPMC13518199

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.