Evidence map›Paper›PMID 42661780›Full record

ArticleFrontiers in cell and developmental biology2026

TNS1/TAGLN-enriched endometrial stromal cells is associated with a persistent fibrotic microenvironment in intrauterine adhesion.

Li Tang, Yutang Li, Siyao Chen, Xueyu Zhao, Shengnan Jiang, Bingzi Jia, Yingli Lu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Li TangDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Yutang LiDepartment of Burn Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.
Siyao ChenDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Xueyu ZhaoDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Shengnan JiangDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Bingzi JiaDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Yingli LuDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrauterine adhesion arise from aberrant repair and fibrotic remodeling after basal endometrial injury. Hysteroscopic adhesiolysis remains the standard treatment, yet postoperative recurrence stays high and durable preventive strategies remain limited. Most studies analyze IUA at the tissue level or in mixed cell populations, leaving the key pathological states and regulatory nodes of endometrial stromal cells insufficiently defined. Here, we integrated bulk transcriptomic data (GSE165321) and single-cell transcriptomic data (GSE215968) from IUA patients and validated findings using a TGF-β1-induced

Indexed as

fibrosishuman endometrial stromal cellintrauterine adhesionoxidative stresstensin 1transgelin

Identifiers

PMID42661780
PMCPMC13518574

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.