Evidence map›Paper›PMID 42661755›Full record

ArticleFrontiers in public health2026

Clinical performance of a novel brief erectile dysfunction scale and comparison with the international index of erectile function-5.

Chengxu Cao, Jian Wang, Zhanghu Li, Bin Cai, Ziyue Zong, Yang Sun, Yun Chen

Abstract readComparative Study
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chengxu CaoDepartment of Andrology, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital of Chinese Medicine, Nanjing, Jiangsu, China.
Jian WangDepartment of Andrology, Yangzhou Hospital of Traditional Chinese Medicine, Yangzhou, Jiangsu, China.
Zhanghu LiDepartment of Andrology, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital of Chinese Medicine, Nanjing, Jiangsu, China.
Bin CaiDepartment of Andrology, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital of Chinese Medicine, Nanjing, Jiangsu, China.
Ziyue ZongDepartment of Andrology, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital of Chinese Medicine, Nanjing, Jiangsu, China.
Yang SunDepartment of Andrology, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital of Chinese Medicine, Nanjing, Jiangsu, China.
Yun ChenDepartment of Andrology, Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Provincial Hospital of Chinese Medicine, Nanjing, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to develop a novel brief erectile dysfunction (ED) scale to serve as a rapid clinical tool for grading ED severity, thereby providing a more concise and efficient diagnostic instrument for routine practice. Methods: A total of 528 eligible patients were enrolled in this study. Each participant independently completed both the novel brief scale and the International Index of Erectile Function-5 (IIEF-5), and subsequently underwent RigiScan monitoring for nocturnal penile tumescence and rigidity (NPTR), intracavernosal injection (ICI) of vasoactive agents, a comprehensive battery of psychological assessments-including the Symptom Checklist-90 (SCL-90), the Eysenck Personality Questionnaire (EPQ), the Hamilton Depression Rating Scale (HAMD), the Hamilton Anxiety Rating Scale (HAMA), and the State-Trait Anxiety Inventory (STAI)-as well as a panel of laboratory tests. The results from all these examinations were compared with the scores obtained from both the brief scale and the IIEF-5 to evaluate the diagnostic performance of the novel instrument. Weighted Cohen's kappa coefficients were calculated to assess the concordance between the two scales in terms of severity classification, and receiver operating characteristic (ROC) curve analysis was performed using RigiScan grading as the reference standard, with the area under the curve (AUC), sensitivity, specificity, and other diagnostic metrics being computed. Results: The brief scale exhibited a strong correlation with the IIEF-5 (Spearman's Conclusions: The novel brief scale may be clinically applicable for assessing ED across a spectrum of severity. It affords the advantages of greater speed and convenience and holds promise as a complementary rapid screening tool for the preliminary assessment of ED.

Indexed as

Erectile DysfunctionSeverity of Illness IndexAdultAgedHumansMaleMiddle AgedROC CurveSensitivity and SpecificitySurveys and Questionnairesbrief scaleclinical studyerectile dysfunctioninternational index of erectile function-5rapid screening tool

Identifiers

PMID42661755
PMCPMC13518213

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.