ArticleFrontiers in public health2026
Subjective symptoms are associated with anxiety in patients with rosacea: a cross-sectional study.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Rosacea, a chronic inflammatory skin disorder, affects patients' physical health. The risk of anxiety disorders in patients with rosacea may be 2-3 times higher than that in the general population. However, the key factors influencing anxiety in rosacea remain unclear, and whether alleviating the subjective symptoms of rosacea can further improve treatment outcomes and quality of life requires further investigation. Methods: A retrospective cross-sectional study of 482 newly diagnosed rosacea patients (West China Hospital) was conducted, with grouping into anxiety/non-anxiety groups for risk factor analysis. After that, a 6-week sub-analysis compared 64 patients receiving conventional carvedilol therapy vs. 32 receiving carvedilol + subjective symptom-targeted treatment, using univariate/multivariate logistic regression and pre-/post-treatment symptom/quality-of-life/psychological status comparisons. Results: Patients with erythematotelangiectatic rosacea (ETR) had significantly higher Hospital Anxiety and Depression Scale-Anxiety (HADS-A) scores ( Conclusion: Subjective symptoms are independently associated with rosacea-related anxiety. Targeted treatment addressing subjective symptoms is associated with improvements in both overall clinical outcomes and psychological status, highlighting the necessity of systematic assessment and management of subjective symptoms in clinical practice.
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