Evidence map›Paper›PMID 42661614›Full record

ArticleJournal of pregnancy2026

Serum Vitamin D Levels in Pregnant Women: The Role of Supplementation on Preterm Infant Outcomes.

Maryam Zakerihamidi, Forough Rakhshanizadeh, Fahimeh Afzaljavan, Hassan Boskabadi

Abstract read
In one paragraph

Article in Journal of pregnancy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maryam ZakerihamidiDepartment of Midwifery, To.C., Islamic Azad University, Tonekabon, Iran, azad.ac.ir.ORCID https://orcid.org/0000-0002-6543-9095
Forough RakhshanizadehDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran, mums.ac.ir.ORCID https://orcid.org/0000-0002-9000-8051
Fahimeh AfzaljavanDepartment of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran, mums.ac.ir.ORCID https://orcid.org/0000-0001-7413-6945
Hassan BoskabadiDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran, mums.ac.ir.ORCID https://orcid.org/0000-0003-4022-5426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveVitamin D plays a crucial role in maternal and infant health. This study was aimed at evaluating and comparing serum vitamin D levels and clinical outcomes between preterm mothers who received vitamin D supplements and those who did not.

methodsIn a cross-sectional study, a total of 328 women were enrolled, of whom 310 mother-infant pairs were included in the final analysis. The supplementation group consisted of mothers who consumed at least 1000 international units of vitamin D daily for a minimum of 1 month prior to delivery. Clinical characteristics and neonatal outcomes were compared between the supplementation and nonsupplementation cohorts.

resultsThe mean serum vitamin D levels were significantly higher in the supplementation group for both mothers (23.88 ± 15.66 vs. 12.68 ± 7.37 ng/mL) and their infants (17.55 ± 12.23 vs. 10.38 ± 7.35 ng/mL; p <0.001 for both). Infants in the nonsupplementation group required resuscitation in the delivery room significantly more often (p = 0.019). Furthermore, the incidence of respiratory distress syndrome (p = 0.002) and respiratory problems (p = 0.004) were significantly higher in the nonsupplemented group. No statistically significant differences were observed regarding one- and fifth-minute Apgar scores (p = 0.200 and p = 0.117), birth weight (p = 0.343), or neonatal mortality (p = 0.062).

conclusionsMaternal vitamin D supplementation is associated with higher serum vitamin D levels in both mothers and preterm infants, as well as a reduced prevalence of adverse neonatal respiratory outcomes. These findings underscore the clinical importance of prenatal vitamin D supplementation to promote maternal and neonatal health, particularly in populations with high rates of vitamin D deficiency.

Indexed as

Dietary SupplementsInfant, PrematureVitamin DVitamin D DeficiencyVitaminsAdultCross-Sectional StudiesFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeRespiratory Distress Syndrome, NewbornVitamin DVitaminsmothersneonatal resuscitationpreterm infantsrespiratory distress syndromesupplementvitamin D

Identifiers

PMID42661614
PMCPMC13522927

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.