ArticleJournal of global health2026
Association between reproductive history and chronic low back pain in the US women: a cross-sectional study.
Article in Journal of global health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Background: Low back pain (LBP) is more prevalent in women, particularly peripartum, suggesting a link between reproductive history and chronic LBP (CLBP). Nationally representative evidence on this association is limited. Methods: We conducted a cross-sectional study using NHANES 1999-2004 and 2009-2010 data. Weighted multivariable logistic regression examined associations between reproductive factors and CLBP. Restricted cubic splines assessed dose-response relationships. Subgroup and sensitivity analyses ensured robustness; multiple imputations addressed missing data. Results: Women with CLBP had a significantly younger age at first live birth (22.01 vs. 23.05 years, P < 0.001) and elevated gravidity and parity. In fully adjusted models, both gravidity (odds ratio (OR) = 1.08; 95% confidence interval (CI) = 1.05-1.10) and parity (OR = 1.07; 95% CI = 1.04-1.11) were positively associated with CLBP, while older age at first (OR = 0.96; 95% CI = 0.94-0.97) and last live birth (OR = 0.97; 95% CI = 0.95-0.98) were associated with lower odds of CLBP. The highest odds were observed in women with a history of pregnancy but no live birth (OR = 2.33; 95% CI = 1.71-3.16). Birth at age ≤16 years was associated with 66% higher odds of CLBP (OR = 1.66; 95% CI = 1.26-2.18). Conclusions: First live birth, higher gravidity and parity, earlier last parity, and pregnancy without live birth are independently associated with a higher CLBP prevalence in women. Integrating reproductive history into pain-related clinical assessment and preventive care may be beneficial for targeted CLBP screening and prevention.
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