Evidence map›Paper›PMID 42661455›Full record

ArticleClinical and translational medicine2026

Overcoming the cytosine base editing barrier: Virus-like particles with uracil-DNA glycosylase inhibition unlocking the clinical potential.

Yuqing Wu, Xingyu Zhu, Junjie Zhu, Jia Chen, Jiaxu Hong

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuqing WuDepartment of Ophthalmology, Eye & ENT Hospital, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Centre for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0006-3718-8838
Xingyu ZhuDepartment of Ophthalmology, Eye & ENT Hospital, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Centre for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0001-8392-369X
Junjie ZhuGene Editing Centre, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Jia ChenGene Editing Centre, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Jiaxu HongDepartment of Ophthalmology, Eye & ENT Hospital, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Centre for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-9912-633X

Funding

National Key Research and Development Program of China 2023YFA0915000National Natural Science Foundation of China 82171102National Science Fund for Distinguished Young Scholars 82425015Shanghai High-Quality Development Plan for Science and Technology Industry 25SF1907000Shanghai Municipal Commission of Health 20254Z0019Shanghai Science and Technology Innovation Action Plan for Advanced Materials 24CL2900802Shanghai Science and Technology Innovation Action Plan for Cell and Gene Therapy 24J22800500the "Dawn" Program of Shanghai Municipal Education Commission 24SG11
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42661455
PMCPMC13522836

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.