Evidence map›Paper›PMID 42661144›Full record

ArticleEmerging infectious diseases2026

Reemergence of Scrub Typhus Associated with Leptotrombidium akamushi Mites and Karp-Like Orientia tsutsugamushi Genotype Bacteria, Japan, 2024-2025.

Motohiko Ogawa, Nobuhiro Takada, Takashi Katayama, Yuki Hashimoto, Kei Nagano, Hirotaka Komine, Yukihiro Akeda

Abstract readCase Reports
In one paragraph

Article in Emerging infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Motohiko Ogawa
Nobuhiro Takada
Takashi Katayama
Yuki Hashimoto
Kei Nagano
Hirotaka Komine
Yukihiro Akeda

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scrub typhus is a miteborne infectious disease caused by Orientia tsutsugamushi bacteria. In Japan, most cases occur in spring and autumn and are transmitted by Leptotrombidium pallidum and L. scutellare mites; summer scrub typhus, transmitted by L. akamushi mites, is rarely reported. In August 2024, a pregnant woman had scrub typhus develop after attending a fireworks event in Niigata Prefecture, Japan, resulting in fetal death. A Vietnam-related Karp-like O. tsutsugamushi genotype, distinct from the Kato type usually associated with L. akamushi mites, was detected from patient samples. Field investigations at the site of the fireworks event revealed seasonal predominance of L. akamushi mites in summer. We detected O. tsutsugamushi sequences identical to the patient's strain in 3 L. akamushi mite larvae and 1 field mouse, suggesting that L. akamushi mites were the source of human infection. Our findings suggest reemergence of summer scrub typhus associated with infected L. akamushi mites carrying a locally novel genotype.

Indexed as

Orientia tsutsugamushiPregnancy Complications, InfectiousScrub TyphusTrombiculidaeAnimalsCommunicable Diseases, EmergingFemaleFetal DeathGenotypeHumansJapanMicePhylogenyPregnancySeasonsApodemus speciosusbacteriaJapanlarge Japanese field mouseLeptotrombidium akamushiOrientia tsutsugamushirickettsiascrub typhusseasonal variationvector-borne infectionszoonoses

Identifiers

PMID42661144
PMCPMC13555703

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.