Evidence map›Paper›PMID 42660916›Full record

ArticleNature communications2026

Neural and computational mechanisms of effort under the pressure of a deadline.

M Andrea Pisauro, Daniele Pollicino, Lucy Fisher, Matthew A J Apps

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

M Andrea PisauroCentre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, UK. andrea.pisauro@plymouth.ac.uk.ORCID 0000-0001-6087-2597
Daniele PollicinoDepartment of Experimental Psychology, University of Oxford, Oxford, UK.
Lucy FisherCentre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, UK.ORCID 0009-0007-7689-4185
Matthew A J AppsCentre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, UK. m.a.j.apps@bham.ac.uk.ORCID 0000-0001-5793-2202

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deadlines fundamentally shape motivation. Research examining effort-based choices finds effort is an avoided cost. However, this overlooks how making progress on longer-term goals to be reached before deadlines motivate people to exert high effort for little immediate reward. Here, we test a framework where motivation depends on deadline pressure (work remaining / time remaining). Across four studies we use computational modelling examining decisions when physical effort makes progress on goals with deadlines. In support of the hypotheses, deadline pressure significantly impacts decision-making, shifting people from avoiding effort, to seeking the progress it makes. Using ultra-high-field fMRI, we show that functionally connected putamen and midcingulate cortex sub-regions process and update estimates of deadline pressure, with distinct anterior cingulate and putamen sub-regions processing effort both when it is being avoided or sought. These results reveal the neurocomputational mechanisms for how deadline pressure shapes motivation, and keep us on track with goals.

Indexed as

Decision MakingMotivationBrain MappingComputer SimulationFemaleGoalsGyrus CinguliHumansMagnetic Resonance ImagingPutamenReward

Identifiers

PMID42660916
PMCPMC13522516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.