Evidence map›Paper›PMID 42660850›Full record

ArticleExperimental physiology2026

Cerebral and peripheral haemodynamics at rest and in response to orthostasis during 3 days of simulated heatwave.

Alexander T Friend, Samuel J Oliver, Lydia L Simpson, Carmen Possnig, Gabriella M K Rossetti, Jason T Fisher, Lydia Tsoutsoubi, Konstantinos Mantzios, Urša Ciuha, Leonidas G Ioannou and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexander T FriendInstitute for Applied Human Physiology, School of Psychology and Sport Science, College of Medicine and Health, Bangor University, Bangor, UK.ORCID https://orcid.org/0000-0001-9533-5732
Samuel J OliverInstitute for Applied Human Physiology, School of Psychology and Sport Science, College of Medicine and Health, Bangor University, Bangor, UK.ORCID https://orcid.org/0000-0002-9971-9546
Lydia L SimpsonBristol Medical School, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0002-0357-6561
Carmen PossnigDepartment of Sports Science, Division of Performance Physiology and Prevention, University of Innsbruck, Innsbruck, Austria.ORCID https://orcid.org/0000-0002-7754-8854
Gabriella M K RossettiInstitute of Sport, Department of Sport and Exercise Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, UK.
Jason T FisherDepartment of Automatics, Biocybernetics and Robotics, Jozef Stefan Institute, Ljubljana, Slovenia.
Lydia TsoutsoubiDepartment of Automatics, Biocybernetics and Robotics, Jozef Stefan Institute, Ljubljana, Slovenia.
Konstantinos MantziosFAME Laboratory, School of Physical Education and Sport Science, University of Thessaly, Trikala, Greece.
Urša CiuhaDepartment of Automatics, Biocybernetics and Robotics, Jozef Stefan Institute, Ljubljana, Slovenia.ORCID https://orcid.org/0000-0001-8382-7449
Leonidas G IoannouDepartment of Automatics, Biocybernetics and Robotics, Jozef Stefan Institute, Ljubljana, Slovenia.
Igor B MekjavicDepartment of Automatics, Biocybernetics and Robotics, Jozef Stefan Institute, Ljubljana, Slovenia.ORCID https://orcid.org/0000-0001-5930-2159
Justin S LawleyDepartment of Sports Science, Division of Performance Physiology and Prevention, University of Innsbruck, Innsbruck, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute heat stress reduces cerebral haemodynamics and orthostatic tolerance. However, the haemodynamic response to orthostasis during prolonged heat stress typical of heatwaves is unknown. We hypothesised that thermoregulatory-induced elevations in peripheral haemodynamics during 3 days of simulated heatwave would exacerbate orthostatic-induced reductions in cerebral haemodynamics observed in temperate conditions. Seven males (22 ± 1 years) maintained a standard work/rest ratio during temperate (∼25.4°C) and heatwave (∼35.4°C) conditions. Gastrointestinal core, mean skin and body (

Indexed as

blood flowcerebralfemoralheat stressheatwaveorthostasisvascular

Identifiers

PMID42660850
PMCPMC13521884

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.