ArticlePloS one2026
Epidemiology and mortality rate of thyroid storm in Thailand: Analysis using a national in-patient database.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the nationwide incidence, temporal trends, of thyroid storm among hospitalized patients with thyrotoxicosis in Thailand, to compare in-hospital mortality between patients with and without thyroid storm, and to identify independent predictors of mortality and healthcare resource utilization among patients with thyroid storm.
methodsA retrospective population-based study was conducted using the National Health Security Office database (2017-2024), including adult patients hospitalized with thyrotoxicosis recorded as the principal diagnosis. Thyroid storm was identified by ICD-10 code E05.5, while other thyrotoxicosis diagnoses without thyroid storm served as the comparator group. Temporal trends in incidence were assessed by Poisson regression, and multivariable logistic regression models identified independent predictors of mortality and prolonged length of hospital stay among patients with thyroid storm.
resultsAmong 4,418 admissions with thyrotoxicosis as the principal diagnosis, 1,160 (26.2%) were thyroid storm and 3,258 (73.8%) were thyrotoxicosis without thyroid storm. The average annual incidence was 0.22 cases per 100,000 person-years, rising from 0.15 (2017) to 0.32 (2024) (p for trend < 0.001). In-hospital mortality was significantly higher in patients with thyroid storm than in those without (18.0% versus 1.0%; p < 0.001). After multivariable adjustment, thyroid storm was independently associated with increased mortality (aOR 11.17; 95% CI 7.41-16.85; p < 0.001). Septic shock (aOR 5.26), cardiogenic shock (aOR 4.90), and acute kidney injury (aOR 3.72) were the strongest independent predictors of death. The median length of hospital stay was 6 days (P25-P75 4-10).
conclusionsThe incidence of thyroid storm in Thailand is rising, with a high in-hospital mortality of 18.0%. Mortality is independently driven by advanced age, male sex, chronic liver disease, and acute multi-organ complications, particularly septic shock, cardiogenic shock, and acute kidney injury. Prolonged hospitalization is largely driven by pneumonia, acute kidney injury, and chronic liver disease. Early recognition and aggressive management of precipitating factors, particularly pneumonia, and expanded insurance coverage for advanced therapies are essential to improve survival.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.